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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
QQ
Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameCearoin
SynonymsCearoin;2,5-Dihydroxy-4-methoxybenzophenone;(2,5-dihydroxy-4-methoxyphenyl)phenylmethanone;Phenyl(2,5-dihydroxy-4-methoxyphenyl)methanone;Methanone, (2,5-dihydroxy-4-methoxyphenyl)phenyl-
CAS52811-37-7
EINECS
Chemical FormulaC14H12O4
Molecular Weight244.24
inchi
Package1 mg
PriceEmail to quote
DescriptionsCearoin

Cearoin

MedChemExpress (MCE)

HY-N8418

52811-37-7

98.0%

4°C, protect from light *In solvent : -80°C, 6 months

Descriptions

Cearoin

Cearoin

MedChemExpress (MCE)

HY-N8418

52811-37-7

98.0%

4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)

Room temperature in continental US
may vary elsewhere.

Cearoin increases autophagy and apoptosis through the production of ROS and the activation of ERK.

Cearoin (10-80 μM) induces cell death in a dose-dependent manner[1]. Cearoin (10-80 μM) increases the phosporylation of ERK in SH-SY5Y cells[1]. Cearoin (5-80 μM) increases the conversion of LC3B-I to LC3B-II in SH-SY5Y cells. The expression of LC3B-II is a good marker for autophagosome formation in the autophagy process[1].

ERK ROS Autophagy Apoptosis

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[1]. Tonking Bastola, et al. Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells. Molecules. 2017 Feb 6
22(2):242. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/cearoin.html
Last Update2025-05-21 16:50:25
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