2-Methylquinazolin-4-ol MedChemExpress (MCE)

Product Name	2-methyl-4(3H)-quinazolinone
Synonyms	b101 B 101 NSC 2757 NSC 12005 AI3-52030 AURORA KA-3754 2-Methylquinazolone Synonyms b101 B 101 NSC 2757 NSC 12005 AI3-52030 AURORA KA-3754 2-Methylquinazolone 2-Methyl-4-quinazolinol 2-Methyl-4-quinazolinone 4-Quinazolinol, 2-methyl- 2-Methyl-chinazolinone(4) 2-methylquinazolin-4(1H)-one 2-Methylquinazolin-4(1H)-one 2-METHYL-4(3H)-QUINAZOLINONE 2-methyl-4(3H)-quinazolinone 2-Methyl-4(3H)-quinazolinone 4-Hydroxy-2-methylquinazoline 4(3H)-Quinazolinone, 2-methyl- 4-Quinazolinol, 2-methyl- (8CI) 2-Methyl-chinazolinone(4) [German] 2-Methyl-1,3-diazanaphthalene-4-ol 2-Methyl-3,4-dihydroquinazoline-4-one 4(1H)-Quinazolinone, 2-methyl- (7CI,9CI)
CAS	1769-24-0;132305-21-6
EINECS	217-189-2
Chemical Formula	C9H8N2O
Molecular Weight	160.17
inchi	InChI=1S/C9H8N2O/c1-6-10-8-5-3-2-4-7(8)9(12)11-6/h2-5H,1H3,(H,10,11,12)
Package	10 mM * 1 mL;500 mg;1 g
Price	Email to quote
Descriptions	2-Methylquinazolin-4-ol 2-Methylquinazolin-4-ol MedChemExpress (MCE) HY-W051513 1769-24-0 97.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions 2-Methylquinazolin-4-ol 2-Methylquinazolin-4-ol MedChemExpress (MCE) HY-W051513 1769-24-0 97.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. 2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM. 2-Methylquinazolin-4-ol inhibits ATCase in a concentration-dependent manner[1]. 2-Methylquinazolin-4-ol (0.2-1 mg i.g. for two days) inhibits ATCase in a dosedependent manner in vivo[2]. \| \| \| \| \| \| \| \| \| \| [1]. S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo). 1991 Jan 44(1):111-2. [Content Brief] [2]. Mahmoud Balbaa, et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J Enzyme Inhib Med Chem. 2008 Aug 23(4):483-92. [Content Brief]
Last Update	2025-04-01 14:45:47

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