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Supplier Contact

Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
QQ
Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameHeme
SynonymsHeme
Heme b
Hematin
Heme irom
Protoheme
Protohaem
NSC 16669

Synonyms

Heme
Heme b
Hematin
Heme irom
Protoheme
Protohaem
NSC 16669
Ferroheme
NSC 267100
ferroheme b
Protoheme IX
Protoheme ix
Reduced hematin
Ferrous protoheme
Iron protoporphyrin
Ferrous protoheme IX
Iron protoporphyrin ix
Ferroprotoporphyrin IX
Iron(II) protoporphyrin IX
(protoporphyrinato)iron(II)
Fe(II) Protoporphyrin IX (Hematin)
FE(II) PROTOPORPHYRIN IX (HEMATIN)
Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-))-
iron(2+) 2,18-bis(2-carboxyethyl)-7,12-diethenyl-3,8,13,17-tetramethylporphine-21,23-diide
Ferrate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24)-, dihydrogen, (SP-4-2)-
Ferrate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kappaN21,kappaN22,kappaN23,kappaN24)-, dihydrogen, (SP-4-2)-
CAS14875-96-8
EINECS604-649-6
Chemical FormulaC34H31FeN4O4-
Molecular Weight615.49
inchiInChI=1/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25
/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42)

inchi

InChI=1/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25
/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42)
/q
+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-
/rC34H32FeN4O4/c1-7-21-17(3)25-13-29-20(6)24(10-12-34(42)43)32-16-28-23(9-11-33(40)41)18(4)26(37-28)14-31-22(8-2)19(5)30(15-27(21)36-25)38(31)35-39(29)32/h7-8,13-16H,1-2,9-12H2,3-6H3,(H,40,41)(H,42,43)/b25-13-,26-14-,27-15-,28-16-,29-13-,30-15-,31-14-,32-16-
Package1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
PriceEmail to quote
DescriptionsFerroheme

Ferroheme

MedChemExpress (MCE)

HY-111914A

14875-96-8

99.70%

-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months

Descriptions

Ferroheme

Ferroheme

MedChemExpress (MCE)

HY-111914A

14875-96-8

99.70%

-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light, stored under nitrogen)

Room temperature in continental US
may vary elsewhere.

Ferroheme is a complex of ferrous ions and porphyrins, which exists in tissues in free form and as a prosthetic group of many heme proteins. In addition, ferroheme is also an isosteric inhibitor of fatty acid binding to rat liver fatty acid binding protein. Feraheme can be used in cardiovascular and neurological disease research..

Feraheme (18 mg/kg, i.v.) reduces the infarct volume and improve the neurological function score in mice with permanent middle cerebral artery occlusion[4].

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[1]. J M Stewart, et al. Ferriheme and ferroheme are isosteric inhibitors of fatty acid binding to rat liver fatty acid binding protein. Biochem Cell Biol. 1996
74(2):249-55.
[Content Brief]

[2]. L Pauling, et al. The Magnetic Properties and Structure of Hemoglobin, Oxyhemoglobin and Carbonmonoxyhemoglobin. Proc Natl Acad Sci U S A. 1936 Apr
22(4):210-6.
[Content Brief]

[3]. Derry P J, et al. The chemical basis of intracerebral hemorrhage and cell toxicity with contributions from eryptosis and ferroptosis[J]. Frontiers in Cellular Neuroscience, 2020, 14: 603043. [Content Brief]

[4]. Zhang B, et al. Effect of Ultramicro Superparamagnetic Iron Oxide Nanoparticles on Cerebral Infarction in Mice. J Nanosci Nanotechnol. 2020 Dec 1
20(12):7305-7310.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/ferroheme.html
Last Update2025-05-21 16:50:25
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