1,2-Dimyristoyl-sn-glycero-3-phosphocholine MedChemExpress (MCE)

Product Name	1,2-dimyristoyl-sn-glycero-3-phospho-choline monohydrate
Synonyms	Dimyristoyl Lecithin L-A-phosphatidylcholine dimyristoyl 1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine 1,2-Dimyristoyl-sn-glycero-3-phosphocholine monohydrate 1,2-dimyristoyl-sn-glycero-3-phospho-choline monohydrate Synonyms Dimyristoyl Lecithin L-A-phosphatidylcholine dimyristoyl 1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine 1,2-Dimyristoyl-sn-glycero-3-phosphocholine monohydrate 1,2-dimyristoyl-sn-glycero-3-phospho-choline monohydrate (2S)-2,3-bis(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate [(2R)-2,3-di(tetradecanoyloxy)propyl] 2-(trimethylammonio)ethyl phosphate
CAS	18194-24-6
EINECS	242-085-9
Chemical Formula	C36H72NO8P
Molecular Weight	677.933
inchi	InChI=1/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1
Package	100 mg;250 mg;500 mg
Price	Email to quote
Descriptions	Colfosceril miristate Colfosceril miristate MedChemExpress (MCE) HY-109541 18194-24-6 DMPC Descriptions Colfosceril miristate Colfosceril miristate MedChemExpress (MCE) HY-109541 18194-24-6 DMPC 1,2-Dimyristoyl-sn-glycero-3-phosphocholine Dimyristoyl phosphatidylcholine 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Colfosceril miristate (DMPC) is a synthetic phospholipid. Colfosceril miristate has antiproliferative effects on various tumors. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery. Colfosceril miristate (20 mM) stabilizes Carmofur at neutral pH (pH= 5-8)[2]. Colfosceril miristate (0.08-250 μM, 72 h) shows cytotoxicity on monolayer tumor cell lines SHSY-5Y, MDA-MB-435s and HT-1080, with IC50s of 214, 231 and 20 μM[2]. Colfosceril miristate (12 h) distinctly enhances the ability of nanoparticles to enter PC-12 cells[3]. Colfosceril miristate (DMPC/PVP-SPIONs solution, 1 mg/mL, 10 μL, injected into the left side of the substantia nigra) could promote the diffusion of SPIONs from the substantia nigra to nearby brain regions in SD rats[3]. \| \| \| \| \| \| \| \| \| \| [1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov 1860(11):2166-2174. [Content Brief]* [2]. Domracheva I, et al. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) increases Carmofur stability and in vitro antiproliferative effect. Toxicol Rep. 2015 Jan 27 2:377-383. [Content Brief] [3]. Han D, et al. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine promotes the adhesion of nanoparticles to bio-membranes and transport in rat brain. RSC Adv. 2021 Nov 3 11(56):35455-35462. [Content Brief]
Supplier Website	https://www.medchemexpress.com/1-2-dimyristoyl-sn-glycero-3-phosphocholine.html
Last Update	2025-05-21 16:50:25

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