1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
MedChemExpress (MCE)
HY-D0178
25952-53-8
99.95%
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)
Room temperature in continental US
may vary elsewhere.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl) is a very useful agent to form amide bonds (peptide bonds) in an aqueous medium[1].?1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC?HCl), is widely used for polyaniline-carbon nanotube preparation for a cholesterol biosensor, precolumn derivatization of aliphatic amines for HPLC, molecular beacons formation for DNA reseach, sensor preparation for calcium detection, the fluorescent determination of carboxylic acids, and solidphase microsequencing of peptides[2].?1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC?HCl) is an aminoaldehyde dehydrogenase (AMADH) inhibitor, while its inhibition on glutamate decarboxylase (GAD) is insignificant[3].
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[1]. Kunihiko Seno, et al. Spectrophotometric determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow injection analysis. Anal Sci. 2008 Apr
24(4):505-8. [Content Brief]
[2]. Kunihiko Seno, et al. Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. Anal Sci. 2009 Mar
25(3):389-93. [Content Brief]
[3]. Runqiang Yang, et al. AMADH inhibitor optimization and its effects on GABA accumulation in soybean sprouts under NaCl-CaCl 2 treatment. 3 Biotech. 2019 May
9(5):184. [Content Brief]