Conessine MedChemExpress (MCE)

Product Name	Conessine
Synonyms	NERIINE;NERVINE;WRIGHTINE;Conessine;ROGUESSINE;n,18-dihydrotrimethyl-conkurchin;3-beta-(dimethylamino)-con-5-enin;n-dimethyl-(3-beta)-con-5-enin-3-amin
CAS	546-06-5
EINECS	208-897-2
Chemical Formula	C24H40N2
Molecular Weight	356.59
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Package	1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Conessine Conessine MedChemExpress (MCE) HY-107566 546-06-5 99.87% -20°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Conessine Conessine MedChemExpress (MCE) HY-107566 546-06-5 99.87% -20°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Conessine, a steroidal alkaloid, is a potent and selective histamine H3 receptor antagonist with Kis of 5.4, 6.0, 5.7 and 25 nM for human, dog, guinea pig, and rat H H3 receptor, respectively. Anti-malarial activity. Plasmodium H3 Receptor 5.4 nM (Ki) rat H3 receptor 25 nM (Ki) Guinea pig H3 Receptor 6.0 nM (Ki) Dog H3 Receptor 5.7 nM (Ki) \| \| \| \| \| \| \| \| \| \| [1]. Santora VJ, et al. A new family of H3 receptor antagonists based on the natural product Conessine. Bioorg Med Chem Lett. 2008 18(4):1490-1494. [Content Brief] [2]. Kim H, et al. Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression [published online ahead of print, 2018 Feb 1]. J Microbiol Biotechnol. 2018 10.4014.jmb.1711.11009. [Content Brief]
Last Update	2025-04-01 14:45:47

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