Cholesteryl oleate-d7 MedChemExpress (MCE)

Product Name	25,26,26,26,27,27,27-heptadeuteriocholest5-en-3ß-ol (9Z-octadecenoate)
Synonyms	18:1 CHOL (D7) ESTER
CAS	1416275-35-8
EINECS
Chemical Formula	C45H78O2
Molecular Weight	651.12
inchi	InChI=1/C45H78O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h14-15,26,35-36,38-42H,7-13,16-25,27-34H2,1-6H3/b15-14-/t36-,38+,39+,40-,41+,42+,44+,45-/s2
Package	1 mg (1.52 mM * 1 mL in Methylene chloride)
Price	Email to quote
Descriptions	Cholesteryl oleate-d7 Cholesteryl oleate-d7 MedChemExpress (MCE) HY-113217S 1416275-35-8 99.0% Solution, -20°C, 2 years Room temperature in continental US Descriptions Cholesteryl oleate-d7 Cholesteryl oleate-d7 MedChemExpress (MCE) HY-113217S 1416275-35-8 99.0% Solution, -20°C, 2 years Room temperature in continental US may vary elsewhere. Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3]. \| \| \| \| \| \| \| \| \| \| [1]. Souza SL, et al. Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid. Chem Phys Lipids. 2011 Oct 164(7):664-71. [Content Brief] [2]. Suñé-Pou M, et, al. Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy. Int J Nanomedicine. 2018 May 30 13:3223-3233. [Content Brief] [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-223. [Content Brief] [4]. Li J, et al. Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer. Sci Rep. 2016 Feb 11 6:20984. [Content Brief]
Last Update	2025-04-01 14:45:47

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