Olopatadine MedChemExpress (MCE)

Product Name	Olopatatadine
Synonyms	KW 4679 Olopatadine OLOPATADINE Olopatatadine a-Hydroxy-Olopatadine -2-(11-(3-(Dimethylamino) 11-((z)-3-(dimethyl-amino)propylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid Synonyms KW 4679 Olopatadine OLOPATADINE Olopatatadine a-Hydroxy-Olopatadine -2-(11-(3-(Dimethylamino) 11-((z)-3-(dimethyl-amino)propylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-
CAS	113806-05-6
EINECS
Chemical Formula	C21H23NO3
Molecular Weight	337.41
inchi
Package	5 mg
Price	Email to quote
Descriptions	Olopatadine Olopatadine MedChemExpress (MCE) HY-W062109 113806-05-6 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Olopatadine Olopatadine MedChemExpress (MCE) HY-W062109 113806-05-6 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis. Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2]. H1 Receptor \| \| \| \| \| \| \| \| \| \| [1]. Kam KW, et al. Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis. Ocul Immunol Inflamm. 2017 Oct 25(5):663-677. [Content Brief] [2]. Leonardi A, et al. Olopatadine: a drug for allergic conjunctivitis targeting the mast cell. Expert Opin Pharmacother. 2010 Apr 11(6):969-81. [Content Brief]
Last Update	2025-04-01 14:45:47

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