YIGSR MedChemExpress (MCE)

Product Name	TYR-ILE-GLY-SER-ARG
Synonyms	Laminin (929-933) TYR-ILE-GLY-SER-ARG H-TYR-ILE-GLY-SER-ARG-OH tyrosyl-isoleucyl-glycyl-seryl-arginine Laminin beta-1 Chain (929-933) (human, mouse) Tyrosinyl-isoleucinyl-glycinyl-serinyl-arginine Synonyms Laminin (929-933) TYR-ILE-GLY-SER-ARG H-TYR-ILE-GLY-SER-ARG-OH tyrosyl-isoleucyl-glycyl-seryl-arginine Laminin beta-1 Chain (929-933) (human, mouse) Tyrosinyl-isoleucinyl-glycinyl-serinyl-arginine Laminin β-1 Chain (929-933) (human, mouse) Tyr-Ile-Gly-Ser-Arg L-Arginine, N2-(N-(N-(N-L-tyrosyl-L-isoleucyl)glycyl)-L-seryl)-
CAS	110590-64-2
EINECS
Chemical Formula	C26H42N8O8
Molecular Weight	594.66
inchi
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Descriptions	YIGSR YIGSR MedChemExpress (MCE) HY-P0132 110590-64-2 Laminin Fragment 929-933 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions YIGSR YIGSR MedChemExpress (MCE) HY-P0132 110590-64-2 Laminin Fragment 929-933 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells. Tyr-Ile-Gly-Ser-Arg \| \| \| \| \| \| \| \| \| \| [1]. N Yoshida, et al. The laminin-derived peptide YIGSR (Tyr–Ile–Gly–Ser–Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice. Br J Cancer. 1999 Aug 80(12): 1898–1904. [2]. Gloe T, et al. The 67-kDa laminin-binding protein is involved in shear stress-dependent endothelial nitric-oxide synthase expression. J Biol Chem. 1999 Jun 4 274(23):15996-6002. [Content Brief]
Last Update	2025-04-01 14:45:47

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