Myrtucommulone A MedChemExpress (MCE)

Product Name	4,4'-[[2,4,6-Trihydroxy-5-(2-methyl-1-oxopropyl)-1,3-phenylene]bis(2-methylpropane-1,1-diyl)]bis[5-hydroxy-2,2,6,6-tetramethyl-4-cyclohexene-1,3-dione]
Synonyms	Myrtucommulone Myrtucommulone A 4,4'-[[2,4,6-Trihydroxy-5-(2-methyl-1-oxopropyl)-1,3-phenylene]bis(2-methylpropane-1,1-diyl)]bis[5-hydroxy-2,2,6,6-tetramethyl-4-cyclohexene-1,3-dione] 4-Cyclohexene-1,3-dione, 4,4'-[[2,4,6-trihydroxy-5-(2-methyl-1-oxopropyl)-1,3-phenylene]bis[(1R)-2-methylpropylidene]]bis[5-hydroxy-2,2,6,6-tetramethyl-
CAS	54247-21-1
EINECS
Chemical Formula	C38H52O10
Molecular Weight	668.81
inchi
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Descriptions	Myrtucommulone A Myrtucommulone A MedChemExpress (MCE) HY-N7196 54247-21-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Myrtucommulone A Myrtucommulone A MedChemExpress (MCE) HY-N7196 54247-21-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Myrtucommulone A is a non-prenylated acylphloroglucinol that can be isolated from Myrtus communis (myrtle). Myrtucommulone A interacts with the HSP60 chaperone and inhibits HSP60 chaperone activity. Myrtucommulone A decreases the expression of LRP130, LONP. Myrtucommulone A (0, 10, 30 µM) decreases the expression of leucine-rich PPR motif-containing protein (LRP130, Lon protease-like protein (LONP) at 37 ℃ and 42 ℃[1]. \| \| \| \| \| \| \| \| \| \| [1]. Wiechmann K, et al. Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone. Cell Chem Biol. 2017 May 18 24(5):614-623.e6. [Content Brief] [2]. Hans M, et al. Stereoisomeric Composition of Natural Myrtucommulone A. J Nat Prod. 2015 Oct 23 78(10):2381-9. [Content Brief]
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Last Update	2025-04-01 14:45:47

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