δ-Sleep Inducing Peptide MedChemExpress (MCE)

Product Name	trp-ala-gly-gly-asp-ala-ser-gly-glu
Synonyms	DSIP Dsip WAGGDASGE EMIDELTIDE SLEEP INDUCING PEPTIDE DELTA SLEEP INDUCING PEPTIDE DELTA SLEEP-INDUCING PEPTIDE 4H2O Synonyms DSIP Dsip WAGGDASGE EMIDELTIDE SLEEP INDUCING PEPTIDE DELTA SLEEP INDUCING PEPTIDE DELTA SLEEP-INDUCING PEPTIDE 4H2O TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU trp-ala-gly-gly-asp-ala-ser-gly-glu TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O tryptophylalanylglycylglycyl-alpha-aspartylalanylserylglycylglutamic acid L-tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid
CAS	62568-57-4
EINECS	211-519-9
Chemical Formula	C35H48N10O15
Molecular Weight	848.82
inchi	InChI=1/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)
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Descriptions	δ-Sleep Inducing Peptide δ-Sleep Inducing Peptide MedChemExpress (MCE) HY-P1501 62568-57-4 Delta-Sleep Inducing Peptide Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions δ-Sleep Inducing Peptide δ-Sleep Inducing Peptide MedChemExpress (MCE) HY-P1501 62568-57-4 Delta-Sleep Inducing Peptide Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties. δ-Sleep Inducing Peptide (DSIP) increases the spindle activity increased in rabbit in vivo, and decreases heart and respiration rate as well. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level[1]. δ-Sleep Inducing Peptide (DSIP 40-360 μg/kg, i.p.) increases catalase and superoxide dismutase (SOD) activities and malonic dialdehyde (MDA) concentration in 40 μg/kg in the liver homogenate of rats subjected to acute stress, but exhibits the opposite effects at 120 μg/kg, and 360 μg/kg[2]. Rats[2] Experiments are performed on male Wistar rats (n = 100) weighing 250-280 g. The animals are divided into groups (10 specimens per group). They are maintained under standard vivarium conditions and have free access to water and food (12:12-h light/dark regimen). δ-Sleep Inducing Peptide is dissolved in physiological saline and injected intraperitoneally 60 min before each stress exposure. Control animals receive an equivalent volume of physiological saline (1 mL/kg). The liver is homogenized in ice-cold physiological saline and centrifuged. The content of LPO products and activities of antioxidant enzymes are measured in the supernatant. LPO intensity is evaluated by malonic dialdehyde (MDA) concentration. Activities of superoxide dismutase (SOD) and catalase are measured spectrophotometrically. The total antioxidant activity (TAA) is evaluated by the method based on inhibition of ascorbate-induced and iron-induced oxidation of Tween-80 to MDA. The assay is conducted on a BTS-330 biochemical analyzer[2]. Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu \| \| \| \| \| \| \| \| \| \| [1]. Monnier M, et al. The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide. Experientia. 1977 Apr 15 33(4):548-52. [Content Brief] [2]. Bobyntsev II, et al. Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bull Exp Biol Med. 2016 Feb 160(4):421-4. [Content Brief]
Last Update	2025-04-01 14:45:47

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