L-Quebrachitol MedChemExpress (MCE)

Product Name	L-Quebrachitol
Synonyms	QUEBRACHITOL;L-QUEBRACHITOL;L-Quebrachitol;(-)-QUEBRACHITOL;3-O-METHYL-L-CHIRO-INOSITOL;2-O-METHYL-L-CHIRO-INOSITOL;1L-2-O-METHYL-CHIRO-INOSITOL;L-CHIRO-INOSITOL 2-METHYL ETHER
CAS	642-38-6
EINECS
Chemical Formula	C7H14O6
Molecular Weight	194.18
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Get quote
Descriptions	L-Quebrachitol L-Quebrachitol MedChemExpress (MCE) HY-N2375 642-38-6 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions L-Quebrachitol L-Quebrachitol MedChemExpress (MCE) HY-N2375 642-38-6 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. L-Quebrachitol is a methoxy analog of inositol isolated from plants, which has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway. L-Quebrachitol (0.01-100 μg/mL , 24-72 h) enhances the cell viability of pre-osteoblastic MC3T3-E1 cells[1]. L-Quebrachitol ( 0.001-10 μg/mL , 48 h) promotes cell DNA synthesis in MC3T3-E1 cells[1]. L-Quebrachitol ( 0.001-10 μg/mL , 48 h) up-regulates mRNA expression of BMP-2, Runx2, osteogenesis markers and increases expression of a gene involved in the MAPK and Wnt/β-Catenin in MC3T3-E1 cells[1]. L-Quebrachitol (0-1.5 mg/mL , 24 h) significantly decreases the cell viability in HepG2 cells[3]. L-Quebrachitol (125 mg/kg) significantly reduces weight gain, increases bone mineral density and bone calcium content of ovariectomized rats[2]. \| \| \| \| \| \| \| \| \| \| [1]. Yodthong T, et al. l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway. Molecules. 2018 Nov 26 23(12). [Content Brief] [2]. Li Y, et al. L-quebrachitol extracted from industrial rubber serum: a study on its antioxidant activities and bone mineral density enhancing functions[J]. Industrial Crops and Products, 2023, 201: 116943. [3]. Mu Y, et al. Sea buckthorn leaf l-quebrachitol extract for improved glucose and lipid metabolism in insulin resistant HepG2 Cells[J]. Bioresources, 2022, 17(1): 527.
Last Update	2025-04-01 14:45:47

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