Aloperine MedChemExpress (MCE)

Product Name	ALOPERINE
Synonyms	ALOPERIN;ALOPERINE;ALLOPTERIN;16,17-didehydro-9-de-2-piperidinyl-,(7-alpha,9-alpha)-ormosanin;(7-alpha,9-alpha)-9-de-2-piperidinyl-16,17-didehydro-ormosanine
CAS	56293-29-9
EINECS	637-202-9
Chemical Formula	C15H24N2
Molecular Weight	232.36
inchi
Package	10 mM * 1 mL;50 mg
Price	Get quote
Descriptions	Aloperine Aloperine MedChemExpress (MCE) HY-13516 56293-29-9 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Aloperine Aloperine MedChemExpress (MCE) HY-13516 56293-29-9 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China. Aloperine induces apoptosis and autophagy in HL-60 cells. Aloperine (1-20 μM 24 hours) gives growth-inhibitory IC50 values in cancer cells ranges from 0.04 to 1.36 mM, the IC50 values in HL-60, U937, K562, EC109, A549 and HepG2 cells are 0.04, 0.27, 0.36, 1.11, 1.18 and 1.36 mM,respectively[1]. Aloperine (1-20 μM 24 hours) induces apoptosis and decreases bcl-2 expression in HL-60 cells[1]. Aloperine (20–100 μM 18 hours) induces autophagy and formation of acidic vacuole in HL-60 cells[1]. \| \| \| \| \| \| \| \| \| \| [1]. Lin Z, et al. In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait. Basic Clin Pharmacol Toxicol. 2011 May 108(5):304-9. [Content Brief] [2]. Yuan XY, et al. Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice. Eur J Pharmacol. 2010 Mar 10 629(1-3):147-52. [Content Brief]
Last Update	2025-04-01 14:45:47

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