Demethyleneberberine MedChemExpress (MCE)

Product Name	Demethyleneberberine
Synonyms	DeMethyleneberberine Demethyleneberberine 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoqu... Dibenzo[a,g]quinoliziniuM,5,6-dihydro-2,3-dihydroxy-9,10-diMethoxy 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium Synonyms DeMethyleneberberine Demethyleneberberine 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoqu... Dibenzo[a,g]quinoliziniuM,5,6-dihydro-2,3-dihydroxy-9,10-diMethoxy 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium 9,10-dimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2,3-diol 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium
CAS	25459-91-0
EINECS
Chemical Formula	C19H18NO4+
Molecular Weight	324.36
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg
Price	Get quote
Descriptions	Demethyleneberberine Demethyleneberberine MedChemExpress (MCE) HY-N0592 25459-91-0 98.0% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Demethyleneberberine Demethyleneberberine MedChemExpress (MCE) HY-N0592 25459-91-0 98.0% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD). \| \| \| \| \| \| \| \| \| \| [1]. Zhang P, et al. Demethyleneberberine, a natural mitochondria-targeted antioxidant, inhibits mitochondrial dysfunction, oxidative stress, and steatosis in alcoholic liver disease mouse model. J Pharmacol Exp Ther. 2015 Jan 352(1):139-47. [Content Brief] [2]. Chen YY, et al. Demethyleneberberine alleviates inflammatory bowel disease in mice through regulating NF-κB signaling and T-helper cell homeostasis. Inflamm Res. 2017 Feb 66(2):187-196. [Content Brief] [3]. Qiang X, et al. Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress. Biochem Biophys Res Commun. 2016 Apr 15 472(4):603-9. [Content Brief]
Last Update	2025-04-01 14:45:47

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