Eniporide MedChemExpress (MCE)

Product Name	ENIPORIDE
Synonyms	ENIPORID ENIPORIDE EMD 96785 EMD 96785,ENIPORIDE N-CarbaMiMidoyl-2-Methyl-5-(Methylsulfonyl)-4-(1H-pyrrol-1-yl)benzaMide N-(diaMinoMethylidene)-2-Methyl-5-Methylsulfonyl-4-pyrrol-1-ylbenzaMide Synonyms ENIPORID ENIPORIDE EMD 96785 EMD 96785,ENIPORIDE N-CarbaMiMidoyl-2-Methyl-5-(Methylsulfonyl)-4-(1H-pyrrol-1-yl)benzaMide N-(diaMinoMethylidene)-2-Methyl-5-Methylsulfonyl-4-pyrrol-1-ylbenzaMide N-(Diaminomethylene)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide N-(Aminoiminomethyl)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide
CAS	176644-21-6
EINECS
Chemical Formula	C14H16N4O3S
Molecular Weight	320.37
inchi
Package	Inquiry
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Descriptions	Eniporide Eniporide MedChemExpress (MCE) HY-106150 176644-21-6 EMD-96785 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Eniporide Eniporide MedChemExpress (MCE) HY-106150 176644-21-6 EMD-96785 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Eniporide (EMD 96785) is a Na(+)/H(+) exchange (NHE) inhibitor. Eniporide specifically inhibits the NHE-1 isoform. Eniporide improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide regulates cardiac performance and high-energy phosphate content in clinically relevant pig models of CPB and cardiac arrest. ENIPORIDE is a potent Na+/H+ exchange inhibitor. Eniporide (3 mg/kg iv systemic infusion before cardioplegia) improves cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest[1]. \| \| \| \| \| \| \| \| \| \| [1]. Zeymer U, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15 38(6):1644-50. [Content Brief] [2]. Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb 77(2):658-63. [Content Brief]
Last Update	2025-04-01 14:45:47

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