Guvacine MedChemExpress (MCE)

Product Name	1,2,5,6-tetrahydropyridine-3-carboxylic acid
Synonyms	GUVACINE GUVACINE-HCL 1,2,5,6-tetrahydronicotinic acid 1,2,5,6-Tetrahydropyridine-3-carboxylic acid 1,2,5,6-tetrahydropyridine-3-carboxylic acid 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid Synonyms GUVACINE GUVACINE-HCL 1,2,5,6-tetrahydronicotinic acid 1,2,5,6-Tetrahydropyridine-3-carboxylic acid 1,2,5,6-tetrahydropyridine-3-carboxylic acid 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro- 3-pyridinecarboxylic acid, 1,2,5,6-tetrahydro- 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
CAS	498-96-4
EINECS
Chemical Formula	C6H9NO2
Molecular Weight	127.14
inchi	InChI=1/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9)
Package	Inquiry
Price	Get quote
Descriptions	Guvacine Guvacine MedChemExpress (MCE) HY-N2482 498-96-4 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Guvacine Guvacine MedChemExpress (MCE) HY-N2482 498-96-4 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively. IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. L A Borden, et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994 Oct 14 269(2):219-24. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-04-01 14:45:47

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-04-01 14:45:47

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-04-01 14:45:47

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-04-01 14:45:47

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-04-01 14:45:47

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-04-01 14:45:47

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-04-01 14:45:47

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact