1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine
MedChemExpress (MCE)
HY-W583869
6418-95-7
1-Stearoyl-2-Oleoyl-sn-glycero-3-PE
18:0-18:1 PE
PE(18:0/18:1)
Please store the product under the recommended conditions in the Certificate of Analysis.
Room temperature in continental US
may vary elsewhere.
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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[1]. Álvarez-Benedicto, E., Farbiak, L., Ramírez, M.M., et al. Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA). Biomater. Sci. 10(2), 549-559 (2022). [Content Brief]
[2]. Tanaka, H., Akita, H., Ishiba, R., et al. Neutral biodegradable lipid-envelope-type nanoparticle using vitamin A-Scaffold for nuclear targeting of plasmid DNA. Biomaterials 35(5), 1755-1761 (2014). [Content Brief]