Meglumine (Excipient) MedChemExpress (MCE)

Product Name	N-Methyl-D-glucamine
Synonyms	Meglumin Meglumine Methylglucamin Methylglucamine n-methylglucamine N-Methyl-D-glucamine D(-)-N-METHYLGLUCAMINE Synonyms Meglumin Meglumine Methylglucamin Methylglucamine n-methylglucamine N-Methyl-D-glucamine D(-)-N-METHYLGLUCAMINE 1-Deoxy-1-(methylamino)hexitol 1-deoxy-1-(methylamino)hexitol 1-deoxy-1-methylamino-D-glucitol 1-deoxy-1-(methylamino)-d-glucito 1-deoxy-1-(methylammonio)-D-allitol 1-deoxy-1-(methylammonio)-D-glucitol 1-deoxy-1-(methylammonio)-D-altritol D-GLUCITOL, 1-DEOXY-1-(METHYLAMINO)- 1-deoxy-1-(methylammonio)-D-mannitol Glucitol, 1-deoxy-1-(methylamino)-, D-
CAS	6284-40-8
EINECS	228-506-9
Chemical Formula	C7H17NO5
Molecular Weight	195.21
inchi	InChI=1/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/p+1/t4-,5-,6+,7-/m1/s1
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Descriptions	Meglumine (Excipient) Meglumine (Excipient) MedChemExpress (MCE) HY-B0342A 6284-40-8 Methylglucamine (Excipient) Descriptions Meglumine (Excipient) Meglumine (Excipient) MedChemExpress (MCE) HY-B0342A 6284-40-8 Methylglucamine (Excipient) Meglumin (Excipient) Methylglucamin (Excipient) Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Meglumine (Methylglucamine) (Excipient) is an orally active amino sugar derived from sorbitol. Meglumine (Excipient) has anti-inflammatory and antitumor activity. Meglumine (Excipient) is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide. Meglumine (Excipient) (40 or 80 mM, 24 h 50 mM, 24 h) dose-dependently reduces the levels of inflammatory factors in THP-1 human myeloid cells and RAW264.7 mouse macrophage cells (Elisa assay)[2]. Meglumine (Excipient) (0-300 mM, 60 min) dose-dependently increases SNARK expression levels in C2C12 mouse myoblasts[4]. Meglumine (Excipient) (25 or 50 mM 37.5 mM, taken orally dissolved in water) reduces levels of inflammatory factors and inhibits skin cancer tumor growth in rats and mice[2]. Meglumine (Excipient) (18 mM, oral gavage) improves muscle function, limits metabolic syndrome, and reduces diabetic complications in type 2 diabetic mice[4]. \| \| \| \| \| \| \| \| \| \| [1]. de Souza ALR, et al. Meglumine-based supra-amphiphile self-assembled in water as a skin drug delivery system: Influence of unfrozen bound water in the system bioadhesiveness. Colloids Surf B Biointerfaces. 2019 Dec 1 184:110523. [Content Brief] [2]. Manley K, et al. Preclinical study of the long-range safety and anti-inflammatory effects of high-dose oral meglumine. J Cell Biochem. 2019 Jul 120(7):12051-12062. [Content Brief] [3]. Guo R Y, et al. Meglumine promoted one-pot, four-component synthesis of pyranopyrazole derivatives. Tetrahedron, 2013, 69(47): 9931-9938. [4]. Bravo-Nuevo A, et al. Meglumine exerts protective effects against features of metabolic syndrome and type II diabetes. PLoS One. 2014 Feb 27 9(2):e90031. [Content Brief]
Last Update	2025-04-01 14:45:47

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