Clevudine MedChemExpress (MCE)

Product Name	1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Synonyms	Levovir Clevudine CLEVUDINE 2'-Fluoro-5-methylarabinosyluracil 1-(2''-DEOXY-2''-FLUORO--L-ARABINOFURANOSYL)-5-METHYLURACIL 1-(2'-DEOXY-2'-FLUORO-BETA-L-ARABINOFURANOSYL)-5-METHYLURACIL 1-[(2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Synonyms Levovir Clevudine CLEVUDINE 2'-Fluoro-5-methylarabinosyluracil 1-(2''-DEOXY-2''-FLUORO--L-ARABINOFURANOSYL)-5-METHYLURACIL 1-(2'-DEOXY-2'-FLUORO-BETA-L-ARABINOFURANOSYL)-5-METHYLURACIL 1-[(2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione 1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
CAS	163252-36-6
EINECS	200-001-2
Chemical Formula	C10H13FN2O5
Molecular Weight	260.22
inchi
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Get quote
Descriptions	Clevudine Clevudine MedChemExpress (MCE) HY-13859 163252-36-6 L-FMAU 99.93% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Clevudine Clevudine MedChemExpress (MCE) HY-13859 163252-36-6 L-FMAU 99.93% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice. Clevudine (L-FMAU) shows some activity against Epstein-Barr virus[2]. \| \| \| \| \| \| \| \| \| \| [1]. Asselah T, et al. Clevudine: a promising therapy for the treatment of chronic hepatitis B. Expert Opin Investig Drugs. 2008 17(12):1963-1974. [Content Brief] [2]. Yoo BC, et al. Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression. Hepatology. 2007 46(4):1041-1048. [Content Brief] [3]. Smee DF, et, al. Progress in the discovery of compounds inhibiting orthopoxviruses in animal models. Antivir Chem Chemother. 2008 19(3):115-24. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

DLin-M-K-DMA

Category: Oligonucleotides
CAS: 1221271-55-1
Last Update: 2025-04-01 14:45:47

6-Azauridine triphosphate

Category: Oligonucleotides
CAS: 6198-30-7
Last Update: 2025-04-01 14:45:47

Cholesterylamine

Category: Oligonucleotides
CAS: 2126-93-4
Last Update: 2025-04-01 14:45:47

5-Formylcytidine

Category: Oligonucleotides
CAS: 148608-53-1
Last Update: 2025-04-01 14:45:47

2'-O-MOE-5MeU-3'-phosphoramidite

Category: Oligonucleotides
CAS: 163878-63-5
Last Update: 2025-04-01 14:45:47

DMT-2'-O-Methylguanosine phosphoramidite

Category: Oligonucleotides
CAS: 1159683-24-5
Last Update: 2025-04-01 14:45:47

DMT-2'-O-Methyladenosine phosphoramidite

Category: Oligonucleotides
CAS: 138906-75-9
Last Update: 2025-04-01 14:45:47

5'-DMTr-dG(iBu)-Methyl phosphonamidite

Category: Oligonucleotides
CAS: 115131-08-3
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact