5-BrdU MedChemExpress (MCE)

Product Name	5-Bromo-2'-deoxyuridine
Synonyms	BRDU 5-budr 5-BRDU Broxuridine bromodeoxyuridine 5'-Bromodeoxyuridine 5-BROMO DEOXYURIDINE Synonyms BRDU 5-budr 5-BRDU Broxuridine bromodeoxyuridine 5'-Bromodeoxyuridine 5-BROMO DEOXYURIDINE 5-BROMO-2'-DEOXYURIDINE 5-Bromo-2'-deoxyuridine 2'-DEOXY-5-BROMOURIDINE 5-BROMO-2'-DESOXYURIDINE 2'-DEOXY-5-BROMOROURIDINE (+)-5-BROMO-2'-DEOXYURIDINE BRDU,5-Bromo-2-deoxyuridine 5-BROMO-1-(2-DEOXY-BETA-D-RIBOFURANOSYL)URACIL 5-bromo-1-(2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
CAS	59-14-3
EINECS	200-415-9
Chemical Formula	C9H11BrN2O5
Molecular Weight	307.1
inchi	InChI=1/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)
Package	10 mM * 1 mL;100 mg;500 mg;1 g
Price	Get quote
Descriptions	5-BrdU 5-BrdU MedChemExpress (MCE) HY-15910 59-14-3 BrdU Descriptions 5-BrdU 5-BrdU MedChemExpress (MCE) HY-15910 59-14-3 BrdU 5-Bromo-2'-deoxyuridine BUdR 99.88% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. 5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells. Bromodeoxyuridine induces a progressive, dose-responsive suppression of cancer cell line and cancer stem cell population expansion RG2 rat glioma cells. In H9 cells and BJ fibroblasts, bromodeoxyuridine alters the cell cycle profile[1]. BrdU is stably integrated into the DNA, and thus can be used in assessment of cell proliferation and other cell procession[2]. Bromodeoxyuridine (300 mg/kg, i.p. or 0.8 mg/mL, p.o.) significantly slows tumor progression in rat glioma RG2 tumor model[1]. Cultures are initially plated at 2000 cells/cm2 and are quantified with a Z2 Coulter Counter. RG2 rat glioma cells are treated once with 0, 1, 10, or 50 µM BrdU for 24 hours, and cumulative growth curves are obtained over 18 days. Control and treated cells are quantified and replated at equal densities on days 5, 12, and 18 after treatment. \| \| \| \| \| \| \| \| \| \| [1]. Levkoff LH, et al. Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Neoplasia. 2008 Aug 10(8):804-16. [Content Brief]* [2]. Rothaeusler K, et al. Assessment of cell proliferation by 5-bromodeoxyuridine (BrdU) labeling for multicolor flow cytometry. Curr Protoc Cytom. 2007 Apr Chapter 7:Unit7.31 [Content Brief]
Last Update	2025-04-01 14:45:47

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