Butylhydroxyanisole MedChemExpress (MCE)

Product Name	Butylated hydroxyanisole
Synonyms	BHA BOA Vertac antioxyne b Butyl Hydroxyanisole 2-butyl-6-methoxyphenol tert-butylhydroxyanisole Synonyms BHA BOA Vertac antioxyne b Butyl Hydroxyanisole 2-butyl-6-methoxyphenol tert-butylhydroxyanisole Butylated hydroxyanisole Butylated hydroxy anisole tert-butyl-4-methoxyphenol tert-butyl-4-hydroxyanisole tert-BUTYLHYDROXYANISOLE TECH 2(3)-tert-Butyl-4-hydroxyanisole 2(3)-t-Butylhydroquinone monomethyl ether BHA butylhydroxyanisole standard(mixture of isomers) tert-Butyl-4-hydroxyanisole (mixture of 2- and 3-isomer) Butylated hydroxyanisoleBHA2(3)-tert-Butyl-4-methoxyphenol3(2)-tert-Butyl-4-hydroxyanisole Butylated hydroxyanisole,2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA
CAS	25013-16-5
EINECS	246-563-8
Chemical Formula	C11H16O2
Molecular Weight	180.24354
inchi	InChI=1/C11H16O2/c1-3-4-6-9-7-5-8-10(13-2)11(9)12/h5,7-8,12H,3-4,6H2,1-2H3
Package	10 mM * 1 mL;500 mg;1 g
Price	Get quote
Descriptions	Butylhydroxyanisole Butylhydroxyanisole MedChemExpress (MCE) HY-B1066 25013-16-5 Butylated hydroxyanisole Descriptions Butylhydroxyanisole Butylhydroxyanisole MedChemExpress (MCE) HY-B1066 25013-16-5 Butylated hydroxyanisole BHA E320 99.78% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development. Butylhydroxyanisole is a ferroptosis inducer. Butylhydroxyanisole exerts neurotoxic effects by promoting cytosolic calcium accumulation and endoplasmic reticulum stress in astrocytes[1]. Butylhydroxyanisole (25-100 μM 48 hours) inhibits growth and induces death in human astrocytes[1]. Butylhydroxyanisole (100 μM 48 hours) decreases the expression of cell-cycle-related proteins and increased the expression of the cell cycle inhibitory protein[1]. Butylhydroxyanisole (100 μM 48 hours) mediates apoptotic signals in NHA-SV40LT Cells[1]. Butylhydroxyanisole also increases the cytosolic calcium level and the expression of endoplasmic reticulum stress proteins[1]. Butylhydroxyanisole induces testicular dysfunction in mouse testis cells by dysregulating calcium homeostasis and stimulating endoplasmic reticulum stress[2]. Butylhydroxyanisole (200 mg/kg i.g. daily for three days) induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice[3]. \| \| \| \| \| \| \| \| \| \| [1]. Sunwoo Park, et al. Butylated Hydroxyanisole Exerts Neurotoxic Effects by Promoting Cytosolic Calcium Accumulation and Endoplasmic Reticulum Stress in Astrocytes. J Agric Food Chem. 2019 Aug 28 67(34):9618-9629. [Content Brief] [2]. Jiyeon Ham, et al. Butylated Hydroxyanisole Exerts Neurotoxic Effects by Promoting Cytosolic Calcium Accumulation and Endoplasmic Reticulum Stress in Astrocytes. Sci Total Environ. 2020 Feb 1 702:134775. [Content Brief] [3]. Lin Luo, et al. Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice. Toxicol Appl Pharmacol. 2015 Nov 1 288(3):339-48. [Content Brief] [4]. Jennifer Yinuo Cao, et al. Mechanisms of ferroptosis. Cell Mol Life Sci. 2016 Jun 73(11-12):2195-209. [Content Brief]
Last Update	2025-04-01 14:45:47

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