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Supplier NameBOC Sciences
ContactLinna Green
Tel+16314854226
Mobile+16314854226
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Emailinfo@bocsci.com
Websitehttps://www.bocsci.com/
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LinkedInhttps://www.linkedin.com/company/boc-sciences
Product NamePlitidepsin
SynonymsAplidin
Plitidepsin
cyclic peptide deriv.
Didemnin A, N-(1-(1,2-dioxopropyl)-L-prolyl)-
2-9-Didemnin B, 2-(1-(1,2-dioxopropyl)-L-proline)-
3,6-Anhydro-(N-{(2S,4S)-4-[(3S,4R,5S)-3-hydroxy-4-{[N-(2-oxo-propanoyl)-L-prolyl-N-Methyl-D-leucyl-L-threonyl]aMino}-5-Methyl-heptanoyloxy]-2,5-diMethyl-3-oxohexanoyl}-L-leucyl-L-prolyl-N

Synonyms

Aplidin
Plitidepsin
cyclic peptide deriv.
Didemnin A, N-(1-(1,2-dioxopropyl)-L-prolyl)-
2-9-Didemnin B, 2-(1-(1,2-dioxopropyl)-L-proline)-
3,6-Anhydro-(N-{(2S,4S)-4-[(3S,4R,5S)-3-hydroxy-4-{[N-(2-oxo-propanoyl)-L-prolyl-N-Methyl-D-leucyl-L-threonyl]aMino}-5-Methyl-heptanoyloxy]-2,5-diMethyl-3-oxohexanoyl}-L-leucyl-L-prolyl-N
L-Tyrosine, 1-(1,2-dioxopropyl)-L-prolyl-N-methyl-D-leucyl-L-threonyl-(3S,4R,5S)-4-amino-3-hydroxy-5-methylheptanoyl-(2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoyl-L-leucyl-L-prolyl-N,o-dimethyl-, (8-3)-lactone
(2S)-N-[(2R)-1-[[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxopentan-2-yl]-N-methyl-1-(2-oxopropanoyl)pyrrolidine-2-carboxamide
CAS137219-37-5
EINECS
Chemical FormulaC57H87N7O15
Molecular Weight1110.34
inchi
Package1 mg
Price$1,099
DescriptionsPlitidepsin
Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.
Supplier Websitehttps://www.bocsci.com/product/plitidepsin-cas-137219-37-5-305469.html
Last Update2025-04-30 11:27:47
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