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Supplier Contact
 | |
| Supplier Name | BOC Sciences |
| Contact | Linna Green |
| Tel | +16314854226 |
| Mobile | +16314854226 |
| info@bocsci.com | |
| Website | https://www.bocsci.com/ |
| https://www.linkedin.com/company/boc-sciences | |
| Product Name | IMetelstat |
| Synonyms | GRN-163L;IMetelstat |
| CAS | 868169-64-6 |
| EINECS | |
| Chemical Formula | |
| Molecular Weight | |
| inchi | |
| Package | 1 mg |
| Price | $2,998 |
| Descriptions | Imetelstat Imetelstat is a telomerase inhibitor, also a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a 'telomerase template antagonist'), a mechanism of action which differs from that for the antisense oligonucleotide-mediated inhibition of telomerase activity through telomerase mRNA binding. Inhibition of telomerase activity in tumor cells by imetelstat results in telomere shortening, which leads to cell cycle arrest or apoptosis. |
| Supplier Website | https://www.bocsci.com/product/imetelstat-cas-868169-64-6-462541.html |
| Last Update | 2025-04-30 11:27:47 |
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