Bendamustine hydrochloride BOC Sciences

Product Name	Bendamustine Hydrochloride
Synonyms	Treanda CYTOSTASAN Bendamustine CytostasanHCl BENDAMUSTINE HCL Phenol,5-iodo-7-methyl- BENDAMUSTIN HYDROCHLORIDE Synonyms Treanda CYTOSTASAN Bendamustine CytostasanHCl BENDAMUSTINE HCL Phenol,5-iodo-7-methyl- BENDAMUSTIN HYDROCHLORIDE Bendamustine Hydrochloride 1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro 1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride 4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride
CAS	3543-75-7;97832-05-8
EINECS
Chemical Formula	C16H21Cl2N3O2.HCl
Molecular Weight	394.72
inchi	InChI=1/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
Package	500 mg
Price	$199
Descriptions	Bendamustine hydrochloride Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group Descriptions Bendamustine hydrochloride Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group a benzimidazole ring, which may act as a purine analogue and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis it may induce mitotic catastrophe and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism.
Supplier Website	https://natuprod.bocsci.com/product/bendamustine-hydrochloride-cas-3543-75-7-66918.html
Last Update	2025-04-30 11:27:47

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