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 | |
| Supplier Name | BOC Sciences |
| Contact | Linna Green |
| Tel | +16314854226 |
| Mobile | +16314854226 |
| info@bocsci.com | |
| Website | https://www.bocsci.com/ |
| https://www.linkedin.com/company/boc-sciences | |
| Product Name | TYRPHOSTIN AG 126 |
| Synonyms | ag127;AG 126;TYRPHOSTIN A10;Tyrphostin 126;TYRPHOSTIN AG 126;RARECHEM AL BX 0673;[3-HYDROXY-4-NITROBENZYLIDENE]MALONONITRILE;ALPHA-CYANO-(3-HYDROXY-4-NITRO)CINNAMONITRILE |
| CAS | 118409-62-4 |
| EINECS | |
| Chemical Formula | C10H5N3O3 |
| Molecular Weight | 215.16 |
| inchi | |
| Package | 100 mg |
| Price | $299 |
| Descriptions | AG 126 Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM . AG 126 may represent a new approach for the therapy of inflammation. |
| Supplier Website | https://www.bocsci.com/ag-126-cas-118409-62-4-item-195904.html |
| Last Update | 2025-04-30 11:27:47 |
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