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Supplier Name | BOC Sciences |
Contact | Linna Green |
Tel | +16314854226 |
Mobile | +16314854226 |
info@bocsci.com | |
Website | https://www.bocsci.com/ |
https://www.linkedin.com/company/boc-sciences |
Product Name | Halofuginone |
Synonyms | trans-l) Halofuginone HALOFUGINONE trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3h)-qui 4(3h)-quinazolinone,7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropy |
CAS | 55837-20-2 |
EINECS | 1806241-263-5 |
Chemical Formula | C16H17BrClN3O3 |
Molecular Weight | 414.68 |
inchi | InChI=1/C16H17BrClN3O3/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14/h5-6,8,14-15,19,23H,1-4,7H2/t14-,15+/m1/s1 |
Package | 100 mg |
Price | $299 |
Descriptions | Halofuginone Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibro-proliferative diseases. |
Supplier Website | https://www.bocsci.com/product/halofuginone-cas-55837-20-2-71625.html |
Last Update | 2025-04-30 11:27:47 |