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Supplier NameBOC Sciences
ContactLinna Green
Tel+16314854226
Mobile+16314854226
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Emailinfo@bocsci.com
Websitehttps://www.bocsci.com/
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LinkedInhttps://www.linkedin.com/company/boc-sciences
Product NameIxabepilone
SynonymsIxempra
IXABEPILONE
Ixabepilone
Ixempra kit
Bms 247550-1
Unii-K27005np0a
Azi-epothilone B

Synonyms

Ixempra
IXABEPILONE
Ixabepilone
Ixempra kit
Bms 247550-1
Unii-K27005np0a
Azi-epothilone B
Aza-epothilone B
(1R,5S,6S,7R,10S,14S,16S)-6,10-Dihydroxy-1,5,7,9,9-pentamethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14.1.0]heptadecane-8,12-dione
(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,9,9-pentamethyl-14-[(E) -1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1.0]heptadecane-8,12-dione
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
CAS219989-84-1
EINECS630-424-7
Chemical FormulaC27H42N2O5S
Molecular Weight506.7
inchiInChI=1/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
Package5 mg
Price$199
DescriptionsIxabepilone
Ixabepilone (also known as azaepothilone B, or BMS-247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Ixabepilone was approved in 2007.
Supplier Websitehttps://www.bocsci.com/product/ixabepilone-cas-219989-84-1-63099.html
Last Update2025-04-30 11:27:47
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