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Supplier NameBOC Sciences
ContactLinna Green
Tel+16314854226
Mobile+16314854226
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Emailinfo@bocsci.com
Websitehttps://www.bocsci.com/
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LinkedInhttps://www.linkedin.com/company/boc-sciences
Product NameLY2784544
SynonymsCS-13
LY2784544
LY2874544
LY 2784544
Gandotinib (LY2784544)
3-(4-chloro-2-fluorobenzyl)-2-Methyl-N-(3-Methyl-1H-pyrazol-5-yl)-8-(MorpholinoMethyl)iMidazo[1,2-b]pyridazin-6-aMine
3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine

Synonyms

CS-13
LY2784544
LY2874544
LY 2784544
Gandotinib (LY2784544)
3-(4-chloro-2-fluorobenzyl)-2-Methyl-N-(3-Methyl-1H-pyrazol-5-yl)-8-(MorpholinoMethyl)iMidazo[1,2-b]pyridazin-6-aMine
3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine
IMidazo[1,2-b]pyridazin-6-aMine, 3-[(4-chloro-2-fluorophenyl)Methyl]-2-Methyl-N-(5-Methyl-1H-pyrazol-3-yl)-8-(4-MorpholinylMethyl)-
CAS1229236-86-5
EINECS
Chemical FormulaC23H25ClFN7O
Molecular Weight469.94
inchi
Package25 mg
Price$439
DescriptionsLY2784544
LY2784544 is a potent and selective JAK2 inhibitor (IC50 = 3 nM), and exhibits less potency against JAK3 (IC50 =48 nM). LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50 = 20 and 55 nM, respectively). It reduces JAK2V617F tumor cell burden with no effect on erythroid progenitor cells.
Supplier Websitehttps://www.bocsci.com/ly2784544-cas-1229236-86-5-item-286343.html
Last Update2025-04-30 11:27:47
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