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intermediate 153 75pharmaceutical intermediates 5Pharmaceutical intermediate 3Chiral catalysts and ligands 1Ibrutinib Intermediate 1
Name CAS Category
Fmoc-L-Lys(Boc)-OH71989-26-9intermediate
1-Boc-3-(aminomethyl)piperidine162167-97-7intermediate
H-Lys(Boc)-OH 2418-95-3intermediate
(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine29841-69-8intermediate
(3S)-(-)-3-(Dimethylamino)pyrrolidine132883-44-4intermediate
(2R,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate309915-46-6intermediate
1-Boc-Piperidine-4-carboxylic Acid84358-13-4intermediate
1-Boc-Piperidine-4-Carboxamide91419-48-6intermediate
(R)-Methyl piperidine-3-carboxylate164323-85-7intermediate
3-Hydroxypiperidine hydrochloride64051-79-2intermediate
(2S,5R)-1-Boc-2,5-dimethylpiperazine548762-66-9intermediate
(S)-Ethyl piperidine-3-carboxylate37675-18-6intermediate
Fmoc-Gly-Gly-OH35665-38-4intermediate
(R)-(-)-NIPECOTIC ACID ETHYL ESTER25137-01-3intermediate
5-Fluoro-2-oxindole56341-41-4intermediate
3-Methyl-3-piperidinol hydrochloride955028-98-5intermediate
(R)-(-)-1-Cbz-3-pyrrolidinol100858-33-1intermediate
tert-butyl (E)-4-(3-(dimethylamino)acryloyl)piperidine-1-carboxylate1799799-87-3intermediate
Fmoc-Asp(OtBu)-OH71989-14-5intermediate
Fmoc-Arg(Pbf)-OH154445-77-9intermediate
Fmoc-Trp(Boc)-OH143824-78-6intermediate
(3S)-(-)-3-Amino-1-Boc-pyrrolidine147081-44-5intermediate
(R)-1-Boc-3-Aminopyrrolidine147081-49-0intermediate
1-Boc-3-aminopyrrolidine186550-13-0intermediate
N-Boc-piperidine-3-methanol116574-71-1intermediate
1-Boc-3-cyano-4-oxopyrrolidine175463-32-8intermediate
1-Boc-3-pyrrolidinone101385-93-7intermediate
(1S,2R)-2-Amino-1,2-diphenylethanol23364-44-5intermediate
(R)-2-Aminocyclohenanol931-16-8intermediate
(1R,2S)-2-Amino-1,2-diphenylethanol23190-16-1intermediate
1-Boc-4-Cyanopiperidine91419-52-2intermediate
4-Boc-aminopiperidine73874-95-0intermediate
Fmoc-Met-OH71989-28-1intermediate
Fmoc-Phe-OH35661-40-6intermediate
Fmoc-Val-OH68858-20-8intermediate
L-Glutamic acid a-tert-butyl ester45120-30-7intermediate
Fmoc-Lys-OH105047-45-8intermediate
Fmoc-Lys-HCL139262-23-0intermediate
Tert-butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate147081-59-2intermediate
1-Cyclopropylpiperazine20327-23-5intermediate
BOC-L-Pyroglutamic Acid Benzyl Ester113400-36-5intermediate
Boc-L-Hydroxyproline13726-69-7intermediate
N-Boc-trans-4-Hydroxy-L-proline methyl ester74844-91-0intermediate
4-hydroxy-1-(4-methylphenyl)sulfonylpyrrolidine-2-carboxylic acid20275-18-7intermediate
O6-Benzylguanine19916-73-5intermediate
(R)-N-Boc-3-pyrrolidineacetic acid204688-60-8Intermediate
L-serine benzyl ester hydrochloride60022-62-0intermediate
(R)-3-(Boc-amino)pyrrolidine122536-77-0intermediate
3-N-Boc-Aminopyrrolidine99724-19-3intermediate
(S)-3-(Boc-Amino)Pyrrolidine122536-76-9intermediate
4-Amino-1-Boc-piperidine87120-72-7intermediate
Fmoc-Glu(OtBu)-OH71989-18-9intermediate
Fmoc-Pro-OH71989-31-6intermediate
Fmoc-Leu-OH35661-60-0intermediate
Fmoc-Gly-OH29022-11-5intermediate
Fmoc-Ile-OH71989-23-6intermediate
Boc-His(Trt)-OH32926-43-5intermediate
Fmoc-Ala-OH35661-39-3intermediate
L-Pipecolicacid83680-83-5intermediate
D(+)-Pipecolinic acid1723-00-8intermediate
Fmoc-His(Boc)-OH81379-52-4intermediate
Fmoc-His(Trt)-OH109425-51-6intermediate
Fmoc-Lys(Boc)-OH71989-26-9intermediate
Fmoc-Cys(Trt)-OH103213-32-7intermediate
Fmoc-Thr(tBu)-OH71989-35-0intermediate
L-1-Boc-Nipecotic acid88495-54-9intermediate
(R)-Boc-Nipecotic acid163438-09-3intermediate
(R)-(+)-1-Benzyl-3-pyrrolidinol101930-07-8intermediate
Fmoc-Tyr(tBu)-OH71989-38-3intermediate
(S)-1-Benzyl-3-pyrrolidinol101385-90-4intermediate
Fmoc-Asn(Trt)-OH132388-59-1intermediate
Fmoc-Lys(Mmt)-OH159857-60-0intermediate
Fmoc-Lys(ivDde)-OH204777-78-6intermediate
H-SER(TBU)-OTBU HCL51537-21-4intermediate
Boc-O-benzyl-L-threonine15260-10-3intermediate
(R)-1-Benzyl-3-hydroxypiperidine91599-81-4intermediate
Boc-L-tert-Leucine62965-35-9intermediate
(S)-3-N-Boc-aminopiperidine216854-23-8intermediate
5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile330792-70-6intermediate
(R)-3-Boc-aminopiperidine309956-78-3intermediate
(S)-1-N-Boc-2-methylpiperazine169447-70-5intermediate
(R)-1-N-Boc-2-methylpiperazine170033-47-3intermediate
(R)-4-Boc-2-methylpiperazine163765-44-4intermediate
Boc-L-aspartic acid 1-benzyl ester30925-18-9intermediate
(S)-(+)-Nipecotic acid59045-82-8intermediate
(R)-1-CBZ-3-PYRROLIDINOL100858-33-1intermediate
(R)-(-)-Nipecotic acid25137-00-2intermediate
(3S)-(+)-3-Aminopyrrolidine Dihydrochloride116183-83-6intermediate
N-Boc-3-Cyanopiperidine91419-53-3intermediate
1-Boc-3-Piperidinone98977-36-7intermediate
Tert-Butyl 4-Acetylpiperidine-1-Carboxylate206989-61-9intermediate
N-Boc-4-Methylenepiperidine159635-49-1intermediate
1-Boc-3-piperidinecarboxylic acid84358-12-3intermediate
N-BOC-4-Hydroxypiperidine109384-19-2intermediate
1-Boc-4-Piperidone79099-07-3intermediate
(R)-3-aminopyrrolidine 2HCl116183-81-4intermediate
N-BOC-3-Aminopiperidine184637-48-7intermediate
Ethyl (S)-3-Piperidinecarboxylate D-Tartrate83602-38-4intermediate
Ethyl (R)-3-Piperidinecarboxylate L-Tartrate167392-57-6intermediate
(S)-(+)-1-Cbz-3-pyrrolidinol100858-32-0intermediate
Boc-L-Dap-OH73259-81-1intermediate
(1S,2S)-(+)-1,2-Diaminocyclohexane21436-03-3intermediate
3-N-Boc-aminopiperidine172603-05-3intermediate
(S)-2-(Aminomethyl)-1-Boc-pyrrolidine119020-01-8intermediate
(1R,2R)-(-)-1,2-Diaminocyclohexane20439-47-8intermediate
(1R,2R)-1,2-diphenylethane-1,2-diamine35132-20-8intermediate
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine151266-23-8intermediate
(S)-1-Boc-piperidine-2-carboxylic acid26250-84-0intermediate
N-alpha-(tert-Butoxycarbonyl)-L-lysine13734-28-6intermediate
N(alpha)-Z-L-lysine2212-75-1intermediate
(R)-(+)-N-Boc-2-piperidinecarboxylic acid28697-17-8intermediate
BOC-D-SER-OME95715-85-8intermediate
Fmoc-Ser(tBu)-OH71989-33-8intermediate
Fmoc-Gln(Trt)-OH132327-80-1intermediate
4-Aminopyrazolo[3,4-d]pyrimidine2380-63-4intermediate
(S)-3-Amino-piperidine-2,6-dione hydrochloride25181-50-4intermediate
N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID126937-41-5intermediate
(S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER1030377-21-9intermediate
1-Boc-4-Aminomethylpiperidine144222-22-0intermediate
1-Boc-4-Methylaminopiperidine147539-41-1intermediate
(R)-1-Boc-3-Aminopiperidine188111-79-7intermediate
(S)-3-Amino-1-N-Boc-piperidine625471-18-3intermediate
Methyl piperidine-3-carboxylate50585-89-2intermediate
(S)-3-Hydroxypyrrolidin-2-one34368-52-0intermediate
N-Boc-O-benzyl-D-serine47173-80-8intermediate
N6-Boc-L-lysine2418-95-3intermediate
(R)-N-Boc-2-Hydroxymethylmorpholine135065-71-3Intermediate
(S)-1-Boc-3-hydroxypiperidine143900-44-1Intermediate
(R)-1-Boc-3-Hydroxypiperidine143900-43-0Intermediate
(S)-3-Hydroxypiperidine hydrochloride475058-41-4Intermediate
(R)-3-Hydroxypiperidine hydrocloride198976-43-1Intermediate
N-(tert-Butoxycarbonyl)-(S)-(+)-3-pyrrolidinol101469-92-5Intermediate
(R)-1-Boc-3-hydroxypyrrolidine109431-87-0Intermediate
(S)-3-Hydroxypyrrolidine hydrochloride122536-94-1Intermediate
(R)-(-)-3-Pyrrolidinol hydrochloride104706-47-0Intermediate
(R)-(+)-2-Piperazinecarboxylic Acid Dihydrochloride126330-90-3Intermediate
(S)-Piperazine-2-carboxylic acid dihydrochloride158663-69-5Intermediate
(R)-1-Boc-3-hydroxymethylpiperazine278788-66-2Intermediate
(S)-1-Boc-3-(hydroxymethyl)piperazine314741-40-7Intermediate
(R)-1,4-Bis(tert-butoxycarbonyl)piperazine-2-carboxylic acid173774-48-6Intermediate
(S)-1,4-Bis(tert-butoxycarbonyl)piperazine-2-carboxylic acid788799-69-9Intermediate
(S)-(+)-2-Methylpiperazine74879-18-8Intermediate
(R)-(-)-2-Methylpiperazine75336-86-6Intermediate
(S)-4-N-Boc-2-methylpiperazine147081-29-6Intermediate
(R)-(+)-2-Tetrahydrofuroic acid87392-05-0Intermediate
(S)-(-)-Tetrahydro-2-furoic acid87392-07-2Intermediate
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine330786-24-8Intermediate
(r)-3-(4-phenoxyphenyl)-1-(piperidin-3yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine1022150-12-4Intermediate
(3R)-1-ethylpiperidin-3-amine dihydrochloride 2031242-60-9Intermediate
2-(1H-benzo[d]imidazol-2-yl)-4-chlorophenol41433-12-9Intermediate
3-Boc-3,9-Diazaspiro[5.5]undecane173405-78-2Intermediate
4-FORMYL-N-CBZ-PIPERIDINE138163-08-3Intermediate
(2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER548762-66-9Intermediate

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