UBCS039
UBCS039(UBCS039)
CAS: 358721-70-7
化学式: C16H13N3
| 中文名 | UBCS039 |
| 英文名 | UBCS039 |
| 别名 | 化合物UBCS039 4-(吡啶-3-基)-4,5-二氢吡咯并[1,2-A]喹喔啉 |
| 英文别名 | UBCS039 4-(Pyridin-3-yl)-4,5-dihydropyrrolo[1,2-a]quinoxaline Pyrrolo[1,2-a]quinoxaline, 4,5-dihydro-4-(3-pyridinyl)- |
| CAS | 358721-70-7 |
| 化学式 | C16H13N3 |
| 分子量 | 247.29 |
| 密度 | 1.25±0.1 g/cm3(Predicted) |
| 沸点 | 453.9±45.0 °C(Predicted) |
| 酸度系数 | 4.66±0.12(Predicted) |
| 存储条件 | 2-8°C |
| 体外研究 | UBCS039 (75 μM, 48 or 72 hours) induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells. UBCS039 leads to autophagosome accumulation in human cancer cells. UBCS039 induces autophagy via AMP-activated protein kinase (AMPK) signaling pathway activation. Western Blot Analysis Cell Line: Human H1299 cells. Concentration: 75 μM. Incubation Time: 48 and 72 hours. Result: Induced deacetylation of SIRT6-targeted histone H3 sites in human H1299 cells. Western Blot Analysis Cell Line: Human H1299 cells. Concentration: 75 μM. Incubation Time: 48 and 72 hours. Result: Induced deacetylation of SIRT6-targeted histone H3 sites in human H1299 cells. Cell Proliferation Assay Cell Line: Human H1299 cells. Concentration: 100 μM. Incubation Time: 48 and 72 hours. Result: Led to a strong decrease of cell proliferation in a dose-dependent manner when compared with control or DMSO-treated cells, starting from day 3 of growth (48 h after treatment) in both H1299 and HeLa cell lines. |
供应商列表
现货供应
产品名: 4-(吡啶-3-基)-4,5-二氢吡咯并[1,2-a]喹喔啉 询盘CAS: 358721-70-7
产地: 上海
包装: 100mg；10mg；1g；250mg；50mg；5mg
规格: 99%
价格: 电话、微信、QQ、邮件
库存: 现货
电话: 400-968-2212
手机: 18916960931
电子邮件: 3623107365@qq.com
QQ: 3623107365
微信: 18916960931
产品描述: 4-(吡啶-3-基)-4,5-二氢吡咯并[1,2-a]喹喔啉,99%,Amole/阿摩尔
现货供应
产品名: 4-(吡啶-3-基)-4,5-二氢吡咯并[1,2-a]喹喔啉 询盘CAS: 358721-70-7
产地: 上海
包装: 100mg；10mg；1g；250mg；50mg；5mg
规格: 99%
价格: 电话、微信、QQ、邮件
库存: 现货
电话: 400-968-2212
手机: 18916960931
电子邮件: 3623107365@qq.com
QQ: 3623107365
微信: 18916960931
产品描述: 4-(吡啶-3-基)-4,5-二氢吡咯并[1,2-a]喹喔啉,99%,Amole/阿摩尔
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