(3-bromo-2-fluoro-phenyl)methanol
(3-bromo-2-fluoro-phenyl)methanol
CAS: 261723-32-4
Molecular Formula: C7H6BrFO
(3-bromo-2-fluoro-phenyl)methanol - Names and Identifiers
(3-bromo-2-fluoro-phenyl)methanol - Physico-chemical Properties
| Molecular Formula | C7H6BrFO |
| Molar Mass | 205.02 |
| Density | 1.658±0.06 g/cm3(Predicted) |
| Melting Point | 36.0 to 40.0 °C |
| Boling Point | 263.2±25.0 °C(Predicted) |
| Flash Point | 112.999°C |
| Vapor Presure | 0.005mmHg at 25°C |
| pKa | 13.80±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.567 |
(3-bromo-2-fluoro-phenyl)methanol - Risk and Safety
| Hazard Class | IRRITANT |
(3-bromo-2-fluoro-phenyl)methanol - Introduction
(3-bromo-2-fluoro-phenyl)methanol is an organic compound with the chemical formula C7H6BrFOH. The following is a description of the properties, uses, preparation and safety information of the compound.
Nature:
(3-bromo-2-fluoro-phenyl)methanol is a colorless to light yellow solid. It has moderate solubility and is insoluble in non-polar solvents (such as diethyl ether) in water, but soluble in polar solvents (such as alcohols and ketones). The melting point and boiling point of this compound are 77-81 ° C. And 209-211 ° C., respectively.
Use:
(3-bromo-2-fluoro-phenyl)methanol is an important organic synthesis intermediate. It can be used to synthesize compounds with pharmaceutical activity, such as anticancer drugs, antiviral drugs and antibacterial agents. In addition, it can also be used as an introducing agent for hydrogen atoms in organic synthesis reactions.
Method:
The preparation of (3-bromo-2-fluoro-phenyl)methanol can be carried out by the following steps:
1.2-fluorobenzyl alcohol and bromine are reacted under alkaline conditions.
2. Extract the reaction mixture and go through appropriate purification steps (such as crystallization or washing) to obtain pure product.
Safety Information:
(3-bromo-2-fluoro-phenyl)methanol is a combustible substance, which may cause combustion when exposed to open flames or high temperatures. Care should be taken to avoid inhalation of its vapor or dust during operation. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary. During use and storage, relevant safety instructions should be followed and appropriate protective measures should be taken, such as wearing protective gloves and goggles. Please store and handle the compound properly to avoid environmental pollution. Consult a professional if necessary.
Nature:
(3-bromo-2-fluoro-phenyl)methanol is a colorless to light yellow solid. It has moderate solubility and is insoluble in non-polar solvents (such as diethyl ether) in water, but soluble in polar solvents (such as alcohols and ketones). The melting point and boiling point of this compound are 77-81 ° C. And 209-211 ° C., respectively.
Use:
(3-bromo-2-fluoro-phenyl)methanol is an important organic synthesis intermediate. It can be used to synthesize compounds with pharmaceutical activity, such as anticancer drugs, antiviral drugs and antibacterial agents. In addition, it can also be used as an introducing agent for hydrogen atoms in organic synthesis reactions.
Method:
The preparation of (3-bromo-2-fluoro-phenyl)methanol can be carried out by the following steps:
1.2-fluorobenzyl alcohol and bromine are reacted under alkaline conditions.
2. Extract the reaction mixture and go through appropriate purification steps (such as crystallization or washing) to obtain pure product.
Safety Information:
(3-bromo-2-fluoro-phenyl)methanol is a combustible substance, which may cause combustion when exposed to open flames or high temperatures. Care should be taken to avoid inhalation of its vapor or dust during operation. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary. During use and storage, relevant safety instructions should be followed and appropriate protective measures should be taken, such as wearing protective gloves and goggles. Please store and handle the compound properly to avoid environmental pollution. Consult a professional if necessary.
Last Update：2024-04-09 20:52:54
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View History
(3-bromo-2-fluoro-phenyl)methanol
BENZO[A]PYRENE-D12
5-Bromo-3-chloro-2-fluorophenol
乳酸氧化酶,
环己基异硫氰酸脂
ERY-TAB
1-溴(正)辛烷
邻甲氧基苯甲酰氯
1-(苄硫基)丙酮
氟哌啶醇
BENZO[A]PYRENE-D12
5-Bromo-3-chloro-2-fluorophenol
乳酸氧化酶,
环己基异硫氰酸脂
ERY-TAB
1-溴(正)辛烷
邻甲氧基苯甲酰氯
1-(苄硫基)丙酮
氟哌啶醇