(6-Chloro-2-pyrazinyl)acetonitrile
(6-Chloro-2-pyrazinyl)acetonitrile
CAS: 1378332-54-7
Molecular Formula: C6H4ClN3
(6-Chloro-2-pyrazinyl)acetonitrile - Names and Identifiers
| Name | (6-Chloro-2-pyrazinyl)acetonitrile |
| Synonyms | (6-Chloro-2-pyrazinyl)acetonitrile 2-(6-Chloropyrazin-2-yl)acetonitrile |
| CAS | 1378332-54-7 |
| InChI | InChI=1S/C6H4ClN3/c7-6-4-9-3-5(10-6)1-2-8/h3-4H,1H2 |
(6-Chloro-2-pyrazinyl)acetonitrile - Physico-chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molar Mass | 153.57 |
| Storage Condition | 2-8°C |
(6-Chloro-2-pyrazinyl)acetonitrile - Introduction
6-Chloropyrazine-2-acetonitrile (English name: 2-pyridyl) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 6-chloropyrazine-2-acetonitrile is a white crystalline solid.
-Molecular formula: C11H6ClN3.
-Molecular weight: 211.64.
-Solubility: Soluble in organic solvents such as acetonitrile, methanol and chloroform.
Use:
6-chloropyrazine-2-acetonitrile has some applications in the field of medicine. It can be used as an intermediate in the synthesis of drugs such as pyranperidone. In addition, it can also be used for other reactions in organic chemical synthesis, such as metal organic catalytic reactions and the construction of complex molecules.
Preparation Method:
The preparation method of 6-chloropyrazine-2-acetonitrile can be carried out by the following steps:
1. First, 2-bromo-6-chloropyridine is reacted with propionitrile in the presence of a base.
2. After the completion of the reaction, the product is obtained by crystallization or other appropriate separation methods.
Safety Information:
When handling 6-chloropyrazine-2-acetonitrile, the following safety information should be noted:
-This compound may be irritating to the eyes and skin, so wear appropriate protective equipment such as lab gloves, goggles and lab coats when handling.
-Inhalation or ingestion of 6-chloropyrazine-2-acetonitrile may be dangerous to health, avoid direct inhalation of its gas or dust.
-It is necessary to operate in a well-ventilated place, and pay attention to avoid contact with other harmful chemicals.
-Observe all relevant safety procedures and legal regulations when using or storing 6-chloropyrazine-2-acetonitrile. In case of any doubt or unforeseen circumstances, professional guidance should be sought immediately.
Nature:
-Appearance: 6-chloropyrazine-2-acetonitrile is a white crystalline solid.
-Molecular formula: C11H6ClN3.
-Molecular weight: 211.64.
-Solubility: Soluble in organic solvents such as acetonitrile, methanol and chloroform.
Use:
6-chloropyrazine-2-acetonitrile has some applications in the field of medicine. It can be used as an intermediate in the synthesis of drugs such as pyranperidone. In addition, it can also be used for other reactions in organic chemical synthesis, such as metal organic catalytic reactions and the construction of complex molecules.
Preparation Method:
The preparation method of 6-chloropyrazine-2-acetonitrile can be carried out by the following steps:
1. First, 2-bromo-6-chloropyridine is reacted with propionitrile in the presence of a base.
2. After the completion of the reaction, the product is obtained by crystallization or other appropriate separation methods.
Safety Information:
When handling 6-chloropyrazine-2-acetonitrile, the following safety information should be noted:
-This compound may be irritating to the eyes and skin, so wear appropriate protective equipment such as lab gloves, goggles and lab coats when handling.
-Inhalation or ingestion of 6-chloropyrazine-2-acetonitrile may be dangerous to health, avoid direct inhalation of its gas or dust.
-It is necessary to operate in a well-ventilated place, and pay attention to avoid contact with other harmful chemicals.
-Observe all relevant safety procedures and legal regulations when using or storing 6-chloropyrazine-2-acetonitrile. In case of any doubt or unforeseen circumstances, professional guidance should be sought immediately.
Last Update：2024-04-09 21:01:54
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