(S)-1-Chloro-2-propanol
(S)-1-Chloro-2-propanol
CAS: 37493-16-6
Molecular Formula: C3H7ClO
(S)-1-Chloro-2-propanol - Names and Identifiers
| Name | (S)-1-Chloro-2-propanol |
| Synonyms | (S)-1-Chloro-2-propa (S)-1-Chloro-2-propanol (S)-1-CHLORO-2-PROPANOL (S)-1-Chloropropan-2-ol (2S)-1-chloropropan-2-ol 2-PROPANOL, 1-CHLORO-, (2S)- |
| CAS | 37493-16-6 |
(S)-1-Chloro-2-propanol - Physico-chemical Properties
| Molecular Formula | C3H7ClO |
| Molar Mass | 94.54 |
(S)-1-Chloro-2-propanol - Introduction
(S)-1-Chloro-2-propanol, chemical formula C3H7ClO, is a chiral molecule with two stereoisomers, of which (S)-1-Chloro-2-propanol is one.
Nature:
(S)-1-Chloro-2-propanol is a colorless liquid with a pungent odor. It has a density of 1.108 g/mL, a boiling point of 123-124°C, and a melting point of <25°C. The substance is soluble in water and ethanol.
Use:
(S)-1-Chloro-2-propanol is widely used in organic synthesis reactions, especially for chiral synthesis and preparation of chiral drugs. It can be used as a raw material or reagent to participate in the esterification of alcohols, etherification, olefin addition and other reactions, and can also be used as a chiral inducer for the preparation of catalysts.
Preparation Method:
(S)-1-Chloro-2-propanol can be prepared by chlorination of (S)-2-propanol, which can be reacted using thionyl chloride or hydrogen chloride as a chlorinating agent.
Safety Information:
(S)-1-Chloro-2-propanol is irritating and may cause irritation to the eyes, skin, respiratory and digestive systems. Wear appropriate personal protective equipment to avoid contact with skin, eyes and mucous membranes. If ingested or inhaled overdose, seek medical attention immediately. At the same time, storage should pay attention to avoid light, sealed, and stored in a dry, well-ventilated place.
Nature:
(S)-1-Chloro-2-propanol is a colorless liquid with a pungent odor. It has a density of 1.108 g/mL, a boiling point of 123-124°C, and a melting point of <25°C. The substance is soluble in water and ethanol.
Use:
(S)-1-Chloro-2-propanol is widely used in organic synthesis reactions, especially for chiral synthesis and preparation of chiral drugs. It can be used as a raw material or reagent to participate in the esterification of alcohols, etherification, olefin addition and other reactions, and can also be used as a chiral inducer for the preparation of catalysts.
Preparation Method:
(S)-1-Chloro-2-propanol can be prepared by chlorination of (S)-2-propanol, which can be reacted using thionyl chloride or hydrogen chloride as a chlorinating agent.
Safety Information:
(S)-1-Chloro-2-propanol is irritating and may cause irritation to the eyes, skin, respiratory and digestive systems. Wear appropriate personal protective equipment to avoid contact with skin, eyes and mucous membranes. If ingested or inhaled overdose, seek medical attention immediately. At the same time, storage should pay attention to avoid light, sealed, and stored in a dry, well-ventilated place.
Last Update：2024-04-09 21:11:58
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