1-(4,5-DIHYDROFURAN-3-YL)-2,2,2-TRIFLUOROETHAN-1-ONE - Names and Identifiers
Name | 1-(4,5-DIHYDROFURAN-3-YL)-2,2,2-TRIFLUOROETHAN-1-ONE
|
Synonyms | 2,3-DIHYDRO-4-(TRIFLUOROACETYL)FURAN 1-(2,3-dihydrofuran-4-yl)-2,2,2-trifluoro-ethanone 1-(4,5-Dihydro-furan-3-yl)-2,2,2-trifluoro-ethanone 1-(4,5-DIHYDROFURAN-3-YL)-2,2,2-TRIFLUOROETHAN-1-ONE Ethanone, 1-(4,5-dihydro-3-furanyl)-2,2,2-trifluoro- Ethanone, 1-(4,5-dihydro-3-furanyl)-2,2,2-trifluoro- (9CI)
|
CAS | 109317-75-1
|
1-(4,5-DIHYDROFURAN-3-YL)-2,2,2-TRIFLUOROETHAN-1-ONE - Physico-chemical Properties
Molecular Formula | C6H5F3O2
|
Molar Mass | 166.1 |
Density | 1.399±0.06 g/cm3(Predicted) |
Boling Point | 48.5 °C |
Storage Condition | Room Temprature |
1-(4,5-DIHYDROFURAN-3-YL)-2,2,2-TRIFLUOROETHAN-1-ONE - Introduction
2,3-Dihydro-4-trifluoroacetylfuran (2,-) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,3-dihydro-4-trifluoroacetylfuran is a colorless to light yellow liquid.
-Solubility: Soluble in common organic solvents, such as ethanol and dimethylformamide.
Use:
-as a reagent: 2,3-dihydro-4-trifluoroacetylfuran is often used as an important reagent in organic synthesis.
-Chemical reaction medium: It can be used for various organic synthesis reactions, such as esterification, etherification and oxidation reactions.
-Drug synthesis: This compound also has a wide range of applications in the field of drug synthesis.
Preparation Method:
The synthesis of 2,3-dihydro-4-trifluoroacetylfuran can be carried out by the following steps:
1. Starting from furan, the acylation reaction was carried out with trifluoroacetic anhydride.
2. the first two hydrogenation reaction, can use lithium aluminum hydride as a reducing agent.
3. Finally, trifluoroacetic acid was added for acylation reaction to obtain the target product.
Safety Information:
The safety information for 2,3-dihydro-4-trifluoroacetylfuran is limited, so use this compound with caution and follow laboratory specifications and chemical safety procedures.
-May cause irritation to skin, eyes and respiratory tract, so contact must be avoided.
-Wear appropriate protective equipment, such as gloves, glasses and a protective mask.
-It should be operated in a well-ventilated laboratory and avoid inhaling its vapors.
-Should be stored in a sealed container, away from fire and oxidizing agents.
-When using, handling or disposing of the compound, comply with local safety regulations and consult a professional body.
Last Update:2024-04-09 20:49:11