1-Hydroxypiperidine
1-Hydroxypiperidine
CAS: 4801-58-5
Molecular Formula: C5H11NO
1-Hydroxypiperidine - Names and Identifiers
| Name | 1-Hydroxypiperidine |
| Synonyms | 1-piperidinol piperidin-1-ol Hydroxypiperidine 1-HYDROXYPIPERDINE N-HYDROXYPIPERIDINE 1-Hydroxypiperidine 1-HYDROXYPIPERIDINE 1-hydroxy-piperidin |
| CAS | 4801-58-5 |
| EINECS | 225-362-9 |
| InChIKey | LKPFBGKZCCBZDK-UHFFFAOYSA-N |
1-Hydroxypiperidine - Physico-chemical Properties
| Molecular Formula | C5H11NO |
| Molar Mass | 101.15 |
| Density | 0.9903 (rough estimate) |
| Melting Point | 37-39°C |
| Boling Point | 146-148℃ (1 Torr) |
| Flash Point | 78°C |
| BRN | 102726 |
| pKa | 14.19±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4550 (estimate) |
| MDL | MFCD00038048 |
| Physical and Chemical Properties | Hygroscopic crystals. Melting point 37-40, boiling point 110-111 ℃(7.33kPa). |
1-Hydroxypiperidine - Risk and Safety
| WGK Germany | 3 |
| RTECS | TN6829550 |
| FLUKA BRAND F CODES | 3-10 |
1-Hydroxypiperidine - Reference Information
| Chemical properties | hygroscopic crystals. Melting point 37-40, boiling point 110-111 deg C (7.33kPa). |
| uses | reagents for peptide synthesis. |
| production method | add 30% ml of hydrogen peroxide to a solution of 226gN-ethylpiperidine and ML of ethanol, reaction was carried out at 0-5 °c for 4H and then at room temperature for 5D to form N-oxo-N-ethylpiperidine. N-ethylpiperidine-N-oxide was heated and melted until vigorous reflux, and ethylene was released, then the 70-90 °c (2.26kPa) fraction was collected by distillation and recrystallized from light petroleum, N-hydroxypiperidine 111g was obtained in a yield of 55%. |
| EPA chemical substance information | information is provided by: ofmpeb.epa.gov (external link) |
Last Update：2024-04-09 21:01:54
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