1000568-14-8

1000568-14-8 - Names and Identifiers

Name	(2-Trifluoromethyl-pyridin-3-yl)-acetic acid
Synonyms	2-TrifluoroMethylpyridine-3-acetic acid 3-Pyridineacetic acid, 2-(trifluoromethyl)- (2-Trifluoromethyl-pyridin-3-yl)-acetic acid 2-[2-(Trifluoromethyl)-3-pyridyl]acetic Acid 2-(2-(trifluoromethyl)pyridin-3-yl)acetic acid
CAS	1000568-14-8

1000568-14-8 - Physico-chemical Properties

Molecular Formula	C8H6F3NO2
Molar Mass	205.13
Density	1.428±0.06 g/cm3(Predicted)
Boling Point	268.4±35.0 °C(Predicted)
pKa	3.83±0.10(Predicted)

1000568-14-8 - Introduction

(2-Trifluoromethyl-pyridin-3-yl)-acetic acid, also known as TFP acid or TFAA, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid

Use:
- TFP acid is commonly used as an acylating reagent in organic synthesis, which can convert anhydrides into corresponding esters.
-It can also be used to adjust the acid-base conditions of chemical reactions and catalyze certain reactions.
- TFP acids are widely used in the preparation of fatty acids, peptides, proteins and other compounds.
-In liquid chromatography analysis, TFP acid is often used as an additive in the mobile phase.

Preparation Method:
(2-Trifluoromethyl-pyridin-3-yl)-acetic acid can be prepared by reacting 2-(trifluoromethyl) pyridin -3-amine with acetic anhydride under appropriate reaction conditions.

Safety Information:
- TFP acid is irritating and corrosive. Pay attention to protective measures when contacting skin and eyes.
-Use should be operated in a well-ventilated place to avoid inhalation of gas and steam.
-Avoid contact with combustibles, away from open flames and heat sources.
-Observe appropriate safety procedures and regulations during storage and handling.