100487-74-9
6-Chloro-5-fluoro-2-oxindole
CAS: 100487-74-9
Molecular Formula: C8H5ClFNO
100487-74-9 - Names and Identifiers
100487-74-9 - Physico-chemical Properties
| Molecular Formula | C8H5ClFNO |
| Molar Mass | 185.58 |
| Density | 1.458 |
| Melting Point | 196-206 °C |
| Boling Point | 327 °C |
| Flash Point | 152 °C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 12.04±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.577 |
100487-74-9 - Introduction
6-Chloro-5-fluoro-1, 3-dihydro-2H-indol-2-one (abbreviated as CFI) is an organic compound. The following is a description of the nature, use, preparation and safety information of CFI:
Nature:
-Appearance: Colorless or pale yellow crystalline solid.
-Melting point: about 80-82°C.
-Boiling point: about 180-182°C.
-Solubility: Almost insoluble in water, soluble in common organic solvents (such as ethanol, dimethylformamide).
Use:
CFI has a wide range of applications, including but not limited to the following:
-Organic synthesis: CFI can be used as an important intermediate for organic synthesis reactions, such as the preparation of indole compounds.
-Drug research: CFI is often used to prepare compound libraries, high-throughput screening, and drug design to find the biological activity of new drugs or compounds.
Preparation Method:
There are many preparation methods for CFI, one of which is commonly used as follows:
Dissolve chloropyran in anhydrous ethanol, add hydrofluoric acid, and then add filtered sodium fluoride. After a period of reaction, filter to remove the precipitate, and add dilute hydrochloric acid to generate crystals.
Safety Information:
- CFI is toxic and should be handled with caution. Avoid contact with skin and eyes during operation, and wear protective gloves, goggles and protective clothing.
-should be away from fire and high heat environment, stored in a dry, well-ventilated place.
-Under no circumstances should it be discharged directly or indirectly into a body of water, soil or sewer.
-If contact or inhalation occurs, immediately flush the affected area with clean water and seek medical help.
Nature:
-Appearance: Colorless or pale yellow crystalline solid.
-Melting point: about 80-82°C.
-Boiling point: about 180-182°C.
-Solubility: Almost insoluble in water, soluble in common organic solvents (such as ethanol, dimethylformamide).
Use:
CFI has a wide range of applications, including but not limited to the following:
-Organic synthesis: CFI can be used as an important intermediate for organic synthesis reactions, such as the preparation of indole compounds.
-Drug research: CFI is often used to prepare compound libraries, high-throughput screening, and drug design to find the biological activity of new drugs or compounds.
Preparation Method:
There are many preparation methods for CFI, one of which is commonly used as follows:
Dissolve chloropyran in anhydrous ethanol, add hydrofluoric acid, and then add filtered sodium fluoride. After a period of reaction, filter to remove the precipitate, and add dilute hydrochloric acid to generate crystals.
Safety Information:
- CFI is toxic and should be handled with caution. Avoid contact with skin and eyes during operation, and wear protective gloves, goggles and protective clothing.
-should be away from fire and high heat environment, stored in a dry, well-ventilated place.
-Under no circumstances should it be discharged directly or indirectly into a body of water, soil or sewer.
-If contact or inhalation occurs, immediately flush the affected area with clean water and seek medical help.
Last Update：2024-04-09 15:17:50
Supplier List
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Request for quotationCAS: 100487-74-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Visit Supplier Webpage Request for quotationCAS: 100487-74-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Visit Supplier Webpage Request for quotationCAS: 100487-74-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 6-Chloro-5-fluoro-2-oxindole Visit Supplier Webpage Request for quotation
CAS: 100487-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 100487-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Request for quotationCAS: 100487-74-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Visit Supplier Webpage Request for quotationCAS: 100487-74-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 6-Chloro-5-fluoroindolin-2-one Visit Supplier Webpage Request for quotationCAS: 100487-74-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 6-Chloro-5-fluoro-2-oxindole Visit Supplier Webpage Request for quotation
CAS: 100487-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 100487-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History