1005474-88-3
5-Fluoro-6-methyl-2-pyridinecarboxylic acid
CAS: 1005474-88-3
Molecular Formula: C7H6FNO2
1005474-88-3 - Names and Identifiers
| Name | 5-Fluoro-6-methyl-2-pyridinecarboxylic acid |
| Synonyms | 5-Fluoro-6-methylpicolinic acid 5-fluoro-6-methylpicolinic acid 5-Fluoro-6-methylpyridine-2-carboxylicacid 5-Fluoro-6-methyl-2-pyridinecarboxylic acid 5-FLUORO-6-METHYLPYRIDINE-2-CARBOXYLIC ACID 2-Pyridinecarboxylic acid, 5-fluoro-6-methyl- |
| CAS | 1005474-88-3 |
| InChI | InChI=1S/C7H6FNO2/c1-4-5(8)2-3-6(9-4)7(10)11/h2-3H,1H3,(H,10,11) |
1005474-88-3 - Physico-chemical Properties
| Molecular Formula | C7H6FNO2 |
| Molar Mass | 155.13 |
| Density | 1.341±0.06 g/cm3(Predicted) |
| Boling Point | 268.8±35.0 °C(Predicted) |
| pKa | 3.65±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
1005474-88-3 - Introduction
5-Fluoro-6-methylpyridine-2-carboxylic acid is an organic compound with the formula C8H6FNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-fluoro-6-methylpyridine-2-carboxylic acid is a colorless or light yellow crystalline solid.
-Melting point: about 140 to 145 degrees Celsius.
-Solubility: It is soluble in water, alcohol and ether and other organic solvents.
Use:
-Chemical Intermediates: 5-Fluoro-6-methylpyridine-2-carboxylic acid is commonly used as an intermediate for the synthesis of other compounds, such as pharmaceuticals, surfactants, dyes and preservatives.
-High-efficiency pesticide: It is also widely used in the agricultural field as a raw material for high-efficiency pesticides.
Preparation Method:
As for the preparation of 5-fluorine -6-methyl pyridine -2-carboxylic acid, the specific preparation method is varied, generally including the following steps:
1. Preparation of 5-fluoro-6-methylpyridine by selective fluorination reaction.
2.5-fluorine -6-methyl pyridine is esterified with appropriate carboxylic acid anhydride to obtain 5-fluorine -6-methyl pyridine -2-carboxylic acid.
Safety Information:
-5-fluoro-6-methylpyridine-2-carboxylic acid is considered to be relatively safe under general operating conditions. However, direct contact with skin and eyes should be avoided if not necessary.
-Wear personal protective equipment such as chemical protective gloves, goggles and protective clothing when using.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-When handling this compound, it is important to follow correct safety practices and strictly follow the relevant safety guidelines.
Nature:
-Appearance: 5-fluoro-6-methylpyridine-2-carboxylic acid is a colorless or light yellow crystalline solid.
-Melting point: about 140 to 145 degrees Celsius.
-Solubility: It is soluble in water, alcohol and ether and other organic solvents.
Use:
-Chemical Intermediates: 5-Fluoro-6-methylpyridine-2-carboxylic acid is commonly used as an intermediate for the synthesis of other compounds, such as pharmaceuticals, surfactants, dyes and preservatives.
-High-efficiency pesticide: It is also widely used in the agricultural field as a raw material for high-efficiency pesticides.
Preparation Method:
As for the preparation of 5-fluorine -6-methyl pyridine -2-carboxylic acid, the specific preparation method is varied, generally including the following steps:
1. Preparation of 5-fluoro-6-methylpyridine by selective fluorination reaction.
2.5-fluorine -6-methyl pyridine is esterified with appropriate carboxylic acid anhydride to obtain 5-fluorine -6-methyl pyridine -2-carboxylic acid.
Safety Information:
-5-fluoro-6-methylpyridine-2-carboxylic acid is considered to be relatively safe under general operating conditions. However, direct contact with skin and eyes should be avoided if not necessary.
-Wear personal protective equipment such as chemical protective gloves, goggles and protective clothing when using.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-When handling this compound, it is important to follow correct safety practices and strictly follow the relevant safety guidelines.
Last Update：2024-04-10 22:29:15
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View History
1005474-88-3
42288-46-0
96515-79-6
13374-31-7
850918-68-2
12225-23-9
702661-85-6
203314-28-7
三乙基氢化锗
6625-20-3
42288-46-0
96515-79-6
13374-31-7
850918-68-2
12225-23-9
702661-85-6
203314-28-7
三乙基氢化锗
6625-20-3