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1006376-62-0

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide

CAS: 1006376-62-0

Molecular Formula: C10H9F2NO

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1006376-62-0 - Names and Identifiers

Name (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide
Synonyms Ticagrelor (1R,2R)-Carboxamide
(1R, 2R) -2- (3, 4-difluorophenyl) Carboxamide
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane carboxamide
(1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxamide
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide
Cyclopropanecarboxamide, 2-(3,4-difluorophenyl)-, (1R,2R)-
CAS 1006376-62-0
EINECS 600-115-1

1006376-62-0 - Physico-chemical Properties

Molecular FormulaC10H9F2NO
Molar Mass197.18
Density1.366±0.06 g/cm3(Predicted)
Melting Point145 - 147°C
Boling Point347.9±42.0 °C(Predicted)
Solubility DMSO (Slightly), Methanol (Slightly)
AppearanceSolid
ColorWhite to Off-White
pKa16.43±0.40(Predicted)
Storage Condition2-8°C
MDLMFCD22380631

1006376-62-0 - Reference Information

ticagrelor ticagrelor (ticagrelor) is an oral antiplatelet drug with the American brand name Brilinta and the European brand name Brilique. ticagrelor is a reversible platelet adenosine diphosphate (ADP) receptor antagonist designed to prevent platelets from sticking together and avoid the formation of blood clots that can lead to heart attacks and strokes.
In the United States, ticagrelor was first approved by FDA in July 2011 for the treatment of adult patients with acute coronary syndrome (ACS). Clinical data show that ticagrelor is significantly better than clopidogrel (clopidogrel) in reducing cardiovascular death within at least 12 months after ACS events. In addition, ticagrelor also reduces the incidence of stent thrombosis (ST) in the patient population who has received stent therapy for ACS.
in June 2020, aslika (AstraZeneca) announced that the us food and drug administration (FDA) has approved anticoagulant Brilinta (ticagrelor) for patients with high-risk coronary artery disease (CAD) to reduce the risk of first heart attack or stroke.
In November 2020, AstraZeneca announced that the U.S. Food and Drug Administration (FDA) has approved anticoagulant Brilinta(ticagrelor, ticagrelor) as a new indication, combined with aspirin, for the treatment of patients with acute ischemic stroke or high-risk transient ischemic attack (TIA), to reduce the risk of subsequent stroke.
Last Update:2024-04-09 20:52:54
1006376-62-0
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Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: Ticagrelor Impurity 82 Request for quotation
CAS: 1006376-62-0
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide Request for quotation
CAS: 1006376-62-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide Visit Supplier Webpage Request for quotation
CAS: 1006376-62-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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