1008402-79-6
Bis-PE21- NHS ester
CAS: 1008402-79-6
Molecular Formula: C30H48N2O17
1008402-79-6 - Names and Identifiers
1008402-79-6 - Physico-chemical Properties
| Molecular Formula | C30H48N2O17 |
| Molar Mass | 708.71 |
| Density | 1.31±0.1 g/cm3(Predicted) |
| Boling Point | 737.0±70.0 °C(Predicted) |
| Appearance | solid or viscous liquid |
| Storage Condition | -20°C |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
1008402-79-6 - Reference Information
| biological activity | Bis-PEG9-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Bis-PEG9-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG9-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | Cleavable PEGs Alkyl/ether |
| in vitro research | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 21:11:58
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