1011-13-8
1-(2-BROMOPHENYL)PIPERAZINE
CAS: 1011-13-8
Molecular Formula: C10H13BrN2
1011-13-8 - Names and Identifiers
| Name | 1-(2-BROMOPHENYL)PIPERAZINE |
| Synonyms | 9-METHYLBENZOTRIAZOLE Vortioxetine impurity B Vortioxetine Impurity 13 1-(2-BROMOPHENYL)PIPERAZINE 1-(2-BROMOPHENYL)-PIPERAZINE Piperazine, 1-(2-bromophenyl)- 1- (2- bromine phenyl) piperazine |
| CAS | 1011-13-8 |
| EINECS | 673-619-2 |
| InChI | InChI=1/C10H13BrN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 |
1011-13-8 - Physico-chemical Properties
| Molecular Formula | C10H13BrN2 |
| Molar Mass | 241.13 |
| Density | 1.386±0.06 g/cm3(Predicted) |
| Boling Point | 94-96°C/0.02mm |
| Flash Point | 157.6°C |
| Vapor Presure | 0.000108mmHg at 25°C |
| pKa | 8.80±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.575 |
1011-13-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
1011-13-8 - Introduction
1-(2-Bromophenyl) piperazine is an organic compound with the chemical formula C12H10BrN. The following is a description of its nature, use, preparation and safety information:
Nature:
1-(2-Bromophenyl) piperazine is a solid with a white crystalline appearance. It has a melting point of about 140-142°C and a boiling point of about 317°C. It is almost insoluble in water at normal temperature, but soluble in organic solvents (e. g., ethanol, chloroform).
Use:
1-(2-Bromophenyl) piperazine is an important intermediate compound, which is often used in organic synthesis. It is often used in the pharmaceutical industry as a raw material for the synthesis of drugs, especially certain antipsychotic and sedative drugs, such as benzodiazepines.
Preparation Method:
The preparation method of 1-(2-bromophenyl) piperazine is usually obtained by reacting p-piperazine with bromobenzene. First, piperazine is reacted with bromobenzene under alkaline conditions, and then after crystallization, separation and purification, the target product is finally obtained.
Safety Information:
1-(2-Bromophenyl) piperazine generally does not cause serious harm under normal conditions of use. However, it is an organic compound with certain toxicity. Appropriate safety precautions should be taken during use or handling to avoid skin contact, inhalation or ingestion. In the use of the process should comply with the operating procedures, wear protective gloves, glasses and protective masks. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Nature:
1-(2-Bromophenyl) piperazine is a solid with a white crystalline appearance. It has a melting point of about 140-142°C and a boiling point of about 317°C. It is almost insoluble in water at normal temperature, but soluble in organic solvents (e. g., ethanol, chloroform).
Use:
1-(2-Bromophenyl) piperazine is an important intermediate compound, which is often used in organic synthesis. It is often used in the pharmaceutical industry as a raw material for the synthesis of drugs, especially certain antipsychotic and sedative drugs, such as benzodiazepines.
Preparation Method:
The preparation method of 1-(2-bromophenyl) piperazine is usually obtained by reacting p-piperazine with bromobenzene. First, piperazine is reacted with bromobenzene under alkaline conditions, and then after crystallization, separation and purification, the target product is finally obtained.
Safety Information:
1-(2-Bromophenyl) piperazine generally does not cause serious harm under normal conditions of use. However, it is an organic compound with certain toxicity. Appropriate safety precautions should be taken during use or handling to avoid skin contact, inhalation or ingestion. In the use of the process should comply with the operating procedures, wear protective gloves, glasses and protective masks. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54
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Product Name: 1-(2-BROMOPHENYL)PIPERAZINE Request for quotationCAS: 1011-13-8
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View History
1011-13-8
媒介紫 1
2298-07-9
硅氯仿
Diethyl propanephosphonate
TANTALUM STANDARD
DI-T-BUTYLNEOPENTYLPHOSPHINE, MIN. 95
3-(4-Chlorophenoxy)pyrrolidine
Dapiprazole HCl
10074-G5
媒介紫 1
2298-07-9
硅氯仿
Diethyl propanephosphonate
TANTALUM STANDARD
DI-T-BUTYLNEOPENTYLPHOSPHINE, MIN. 95
3-(4-Chlorophenoxy)pyrrolidine
Dapiprazole HCl
10074-G5