1012-05-1
dl-homophenylalanine
CAS: 1012-05-1
Molecular Formula: C10H13NO2
1012-05-1 - Names and Identifiers
| Name | dl-homophenylalanine |
| Synonyms | H-DL-HoPhe-OH H-DL-Homophe-OH dl-homophenylalanine Lisinopril EP IMpurity A 2-AMINO-4-PHENYL-BUTYRIC ACID 2-aMino-4-(3-pyridyl)butanoic acid 2-amino-4-(3-pyridyl)butanoic acid Enalapril Homophenylalanine Impurity 1-carboxy-1-iMino-3-phenylpropan-2-yl |
| CAS | 1012-05-1 |
| InChI | InChI=1/C9H12N2O2/c10-8(9(12)13)4-3-7-2-1-5-11-6-7/h1-2,5-6,8H,3-4,10H2,(H,12,13) |
1012-05-1 - Physico-chemical Properties
| Molecular Formula | C10H13NO2 |
| Molar Mass | 179.22 |
| Density | 1.164±0.06 g/cm3(Predicted) |
| Melting Point | 282°C (dec.)(lit.) |
| Boling Point | 324.8±35.0 °C(Predicted) |
| Flash Point | 170.5°C |
| Solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
| Vapor Presure | 9.3E-06mmHg at 25°C |
| Appearance | White powder or block |
| Color | White to Off-White |
| pKa | 2.32±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.569 |
| MDL | MFCD00063092 |
1012-05-1 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29224999 |
1012-05-1 - Introduction
DL-homophenylalanine is an amino acid with the chemical name 2-phenylalanine. Its structure contains phenylpropylamino and carboxyl functional groups.
DL-homophenylalanine is a white crystalline powder, soluble in water and alcohol solvents. Its pH is in the acidic range, about 2.2-2.8. DL-homophenylalanine is a raw material for protein synthesis, which can form polypeptide chains by combining with other amino acids and participate in metabolic processes in the body.
The main applications of DL-homophenylalanine are in the pharmaceutical and food industries. In medicine, it can be used to synthesize drugs, such as anti-tumor drugs, thrombolytic drugs, anti-anxiety drugs, etc. In the food industry, it can be used as a food additive to enhance the nutritional value of food.
The production method of DL-homophenylalanine is usually achieved by chemical synthesis. A commonly used synthetic method is to obtain DL-homophenylalanine through the steps of phenylacetone and substitution reaction and carboxylation reaction.
In terms of safety, DL-homophenylalanine is generally safe in normal amounts. However, excessive intake may cause adverse reactions to individual groups, such as headache, gastrointestinal discomfort and so on. Therefore, when using or applying, it should be operated in accordance with the relevant dosage requirements and safe operation specifications.
However, it should be noted that DL-high phenylalanine is contraindicated for some people with phenylketonuria. Phenylketonuria is a genetic metabolic disease. Patients lack phenylacetone hydroxylase and cannot metabolize amino acids such as phenylalanine. Therefore, patients should avoid taking DL-high phenylalanine. Before use, it is recommended to consult a doctor or professional for advice.
DL-homophenylalanine is a white crystalline powder, soluble in water and alcohol solvents. Its pH is in the acidic range, about 2.2-2.8. DL-homophenylalanine is a raw material for protein synthesis, which can form polypeptide chains by combining with other amino acids and participate in metabolic processes in the body.
The main applications of DL-homophenylalanine are in the pharmaceutical and food industries. In medicine, it can be used to synthesize drugs, such as anti-tumor drugs, thrombolytic drugs, anti-anxiety drugs, etc. In the food industry, it can be used as a food additive to enhance the nutritional value of food.
The production method of DL-homophenylalanine is usually achieved by chemical synthesis. A commonly used synthetic method is to obtain DL-homophenylalanine through the steps of phenylacetone and substitution reaction and carboxylation reaction.
In terms of safety, DL-homophenylalanine is generally safe in normal amounts. However, excessive intake may cause adverse reactions to individual groups, such as headache, gastrointestinal discomfort and so on. Therefore, when using or applying, it should be operated in accordance with the relevant dosage requirements and safe operation specifications.
However, it should be noted that DL-high phenylalanine is contraindicated for some people with phenylketonuria. Phenylketonuria is a genetic metabolic disease. Patients lack phenylacetone hydroxylase and cannot metabolize amino acids such as phenylalanine. Therefore, patients should avoid taking DL-high phenylalanine. Before use, it is recommended to consult a doctor or professional for advice.
Last Update：2024-04-09 20:49:11
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