101376-26-5
(R)-4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
CAS: 101376-26-5
Molecular Formula: C12H17NO2
101376-26-5 - Names and Identifiers
| Name | (R)-4-BENZYL-3-HYDROXYMETHYLMORPHOLINE |
| Synonyms | (R)-(4-BenzylMorpholin-3-yl)Methanol [(3R)-4-benzylMorpholin-3-yl]Methanol [(3R)-4-Benzylmorpholin-3-yl]methanol (R)-4-Benzyl-3-hydroxymethyloorpholine (R)-4-Benzly-3-hydroxymethylmorpholine (R)-4-BENZYL-3-HYDROXYMETHYLMORPHOLINE (R)-4-(phenylmethyl)-3-Morpholinemethanol (3R)-4-(Phenylmethyl)-3-morpholinemethanol 3-Morpholinemethanol, 4-(phenylmethyl)-, (3R)- |
| CAS | 101376-26-5 |
| InChI | InChI=1/C12H17NO2/c14-9-12-10-15-7-6-13(12)8-11-4-2-1-3-5-11/h1-5,12,14H,6-10H2/t12-/m1/s1 |
101376-26-5 - Physico-chemical Properties
| Molecular Formula | C12H17NO2 |
| Molar Mass | 207.27 |
| Density | 1.117±0.06 g/cm3(Predicted) |
| Melting Point | 229-230 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) |
| Boling Point | 322.7±22.0 °C(Predicted) |
| Flash Point | 149°C |
| Vapor Presure | 0.000113mmHg at 25°C |
| pKa | 14.85±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.549 |
101376-26-5 - Introduction
(R)-4-Benzyl-morpholine-3-methanol is an organic compound also known as (R)-4-benzylmorpholin-3-ol. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless or yellowish crystal
-Molecular formula: C12H17NO2
-Molecular weight: 207.27g/mol
-Melting point: 76-80 degrees Celsius
-Boiling point: 424.8 degrees Celsius
-Solubility: Can be dissolved in many organic solvents, such as ethanol and dimethyl sulfoxide
Use:
-as an organic synthesis intermediate:(R)-4-benzyl-morpholine-3-methanol can be used as an organic synthesis intermediate, which can participate in the manufacture of synthetic drugs, pesticides and dyes.
-Diffusion blocker:(R)-4-benzyl-morpholine-3-methanol is used as a diffusion blocker in some pesticides to improve its effect by preventing the migration of drugs in plants.
Preparation Method:
The preparation method of (R)-4-benzyl-morpholine-3-methanol can be achieved by the following steps:
1. (R)-4-oxomorpholine is reacted with an alkaline reducing agent (such as sodium hydroxide) to obtain (R)-4-benzyl-morpholine.
2. (R)-4-benzyl-morpholine is reacted with an aldehyde (such as acetaldehyde) under acidic conditions to generate (R)-4-benzyl-morpholine-3-methanol.
Safety Information:
(R)-4-Benzyl-morpholine-3-methanol has limited safety information. The following should be noted when using:
-May be irritating to eyes and skin, rinse with plenty of water immediately after contact.
-Wear appropriate protective gloves and eye protection when in use.
-Avoid inhaling aerosols or dust, and provide good ventilation during use.
-Keep separate from oxidant and strong acid/alkali.
-Store in a dry, cool, well-ventilated place, away from fire and flammable substances.
-When using and disposing, please follow local regulations and safe operating procedures.
Nature:
-Appearance: colorless or yellowish crystal
-Molecular formula: C12H17NO2
-Molecular weight: 207.27g/mol
-Melting point: 76-80 degrees Celsius
-Boiling point: 424.8 degrees Celsius
-Solubility: Can be dissolved in many organic solvents, such as ethanol and dimethyl sulfoxide
Use:
-as an organic synthesis intermediate:(R)-4-benzyl-morpholine-3-methanol can be used as an organic synthesis intermediate, which can participate in the manufacture of synthetic drugs, pesticides and dyes.
-Diffusion blocker:(R)-4-benzyl-morpholine-3-methanol is used as a diffusion blocker in some pesticides to improve its effect by preventing the migration of drugs in plants.
Preparation Method:
The preparation method of (R)-4-benzyl-morpholine-3-methanol can be achieved by the following steps:
1. (R)-4-oxomorpholine is reacted with an alkaline reducing agent (such as sodium hydroxide) to obtain (R)-4-benzyl-morpholine.
2. (R)-4-benzyl-morpholine is reacted with an aldehyde (such as acetaldehyde) under acidic conditions to generate (R)-4-benzyl-morpholine-3-methanol.
Safety Information:
(R)-4-Benzyl-morpholine-3-methanol has limited safety information. The following should be noted when using:
-May be irritating to eyes and skin, rinse with plenty of water immediately after contact.
-Wear appropriate protective gloves and eye protection when in use.
-Avoid inhaling aerosols or dust, and provide good ventilation during use.
-Keep separate from oxidant and strong acid/alkali.
-Store in a dry, cool, well-ventilated place, away from fire and flammable substances.
-When using and disposing, please follow local regulations and safe operating procedures.
Last Update：2024-04-09 02:00:40
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CAS: 101376-26-5
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View History
101376-26-5
192863-40-4
38971-41-4
12402-95-8
1820565-69-2
1393845-83-4
1575-61-7
28211-04-3
403860-66-2
887591-96-0
192863-40-4
38971-41-4
12402-95-8
1820565-69-2
1393845-83-4
1575-61-7
28211-04-3
403860-66-2
887591-96-0