101711-78-8
(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
CAS: 101711-78-8
Molecular Formula: C13H15NO3
101711-78-8 - Names and Identifiers
| Name | (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone |
| Synonyms | N-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE (S)-4-benzyl-3-propionyl-2-oxazolidinone (S)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE N-3-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE (S)-(+)-4-BENZYL-3-PROPIONYL-2-OXALIDINONE (4s)-(+)-benzyl-3-propionyl-2-oxazolidinone (S)-(+)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE (4S)-4-Benzyl-3-propanoyl-1,3-oxazolidin-2-on (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone (4S)-4-benzyl-3-propanoyl-1,3-oxazolidin-2-one (4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one 2-Oxazolidinone, 3-(1-oxopropyl)-4-(phenylmethyl)-, (4S)- |
| CAS | 101711-78-8 |
| InChI | InChI=1/C13H15NO3/c1-2-12(15)14-11(9-17-13(14)16)8-10-6-4-3-5-7-10/h3-7,11H,2,8-9H2,1H3/t11-/m0/s1 |
| InChIKey | WHOBYFHKONUTMW-NSHDSACASA-N |
101711-78-8 - Physico-chemical Properties
| Molecular Formula | C13H15NO3 |
| Molar Mass | 233.26 |
| Density | 1.1475 (rough estimate) |
| Melting Point | 42-44 °C |
| Boling Point | 375.51°C (rough estimate) |
| Specific Rotation(α) | 97 º (c=1, EtOH) |
| Flash Point | 193.7°C |
| Solubility | Chloroform, Methanol |
| Vapor Presure | 1.68E-06mmHg at 25°C |
| Appearance | White powder or solid |
| Color | Off-White to Pale Yellow |
| pKa | -2.35±0.40(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 103 ° (C=1, EtOH) |
| MDL | MFCD00269688 |
| Physical and Chemical Properties | Melting point 42-46°C specific rotation 97 ° (c = 1, EtOH) |
101711-78-8 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R43 - May cause sensitization by skin contact |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| HS Code | 29349990 |
101711-78-8 - Introduction
(S)-4-Benzyl-3-propanoyl-2-oxazolidinone, also known as (S)-Blebbistatin, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
(S)-4-Benzyl-3-propanoyl-2-oxazolidinone is a colorless crystalline solid. Its molecular formula is C18H16N2O2 and its molecular weight is 292.33. It has good solubility and can be dissolved in ethanol, dimethylsulfinamide and dimethyl sulfoxide, but it is poorly soluble in water.
Use:
(S)-4-Benzyl-3-propanoyl-2-oxazolidinone is commonly used in biochemical research and laboratory applications. It is a potent actin carnosine uncoupling agent that selectively inhibits actin II heavy chain ATPase activity, thereby inhibiting the contraction of striated muscle. Therefore, in cell and animal models, it is often used to study the physiological and pathological mechanisms of muscle contraction and movement, especially the study of diseases related to myocardial contraction.
Preparation Method:
The preparation method of (S)-4-benzyl -3-propionyl -2-oxazolidinone is relatively complicated and is generally completed by chemical synthesis. In brief, its preparation includes the construction of oxazole ring, the introduction of benzyl group and the introduction of propionyl group. Detailed synthetic methods can be found in the relevant chemical literature or patents.
Safety Information:
(S)-4-benzyl -3-propionyl -2-oxazolidinone is generally safe when used correctly. However, there are certain safe practices that need to be followed for any chemical. It is an organic compound that may cause irritation to the respiratory system, skin and eyes. During operation, avoid inhaling its dust or solution, avoid contact with skin and eyes, and maintain good ventilation conditions. Wear appropriate protective gloves and glasses during use. If there is an accident, please seek medical help in time.
Nature:
(S)-4-Benzyl-3-propanoyl-2-oxazolidinone is a colorless crystalline solid. Its molecular formula is C18H16N2O2 and its molecular weight is 292.33. It has good solubility and can be dissolved in ethanol, dimethylsulfinamide and dimethyl sulfoxide, but it is poorly soluble in water.
Use:
(S)-4-Benzyl-3-propanoyl-2-oxazolidinone is commonly used in biochemical research and laboratory applications. It is a potent actin carnosine uncoupling agent that selectively inhibits actin II heavy chain ATPase activity, thereby inhibiting the contraction of striated muscle. Therefore, in cell and animal models, it is often used to study the physiological and pathological mechanisms of muscle contraction and movement, especially the study of diseases related to myocardial contraction.
Preparation Method:
The preparation method of (S)-4-benzyl -3-propionyl -2-oxazolidinone is relatively complicated and is generally completed by chemical synthesis. In brief, its preparation includes the construction of oxazole ring, the introduction of benzyl group and the introduction of propionyl group. Detailed synthetic methods can be found in the relevant chemical literature or patents.
Safety Information:
(S)-4-benzyl -3-propionyl -2-oxazolidinone is generally safe when used correctly. However, there are certain safe practices that need to be followed for any chemical. It is an organic compound that may cause irritation to the respiratory system, skin and eyes. During operation, avoid inhaling its dust or solution, avoid contact with skin and eyes, and maintain good ventilation conditions. Wear appropriate protective gloves and glasses during use. If there is an accident, please seek medical help in time.
Last Update：2024-04-10 22:29:15
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Tel: +86-400-900-4166
Email: product@acmec-e.com
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Product Name: (4S)-(+)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE Visit Supplier Webpage Request for quotationCAS: 101711-78-8
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Product Name: (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone Visit Supplier Webpage Request for quotationCAS: 101711-78-8
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