102185-33-1
5-Bromo-4-chloro-3-indolyl phosphate, disodium salt
CAS: 102185-33-1
Molecular Formula: C8H4BrClNNa2O4P
102185-33-1 - Names and Identifiers
102185-33-1 - Physico-chemical Properties
| Molecular Formula | C8H4BrClNNa2O4P |
| Molar Mass | 370.43 |
| Melting Point | 300°C |
| Boling Point | 580.2°C at 760 mmHg |
| Flash Point | 304.7°C |
| Water Solubility | Soluble in water and toluene. |
| Solubility | H2O: 20mg/mL |
| Vapor Presure | 2.65E-14mmHg at 25°C |
| Appearance | White to light blue powder |
| Color | Clear pale yellow to yellow |
| Storage Condition | -20°C |
| Sensitive | Moisture & Light Sensitive |
| MDL | MFCD00036757 |
102185-33-1 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10-21 |
| HS Code | 29339190 |
102185-33-1 - Reference
| Reference Show more | 1. [IF=10.618] Wenjia Liu et al."A Point-of-Need infrared mediated PCR platform with compatible lateral flow strip for HPV detection."Biosens Bioelectron. 2017 Oct;96:213 |
102185-33-1 - Introduction
5-Bromo-4-chloro-3-indolyl sodium phosphate (5-Bromo-4-chloro-3-indolyl phosphate sodium) is a commonly used chemical reagent with the following properties:
1. appearance: white solid powder.
2. Solubility: Soluble in polar solvents such as water, methanol and ethanol.
3. stability: stable in dry and anhydrous environment, but will gradually decompose in high humidity environment.
5-Bromo-4-chloro-3-indolyl sodium phosphate is usually used in biological experiments such as enzyme labeling reagents and chemiluminescence detection. Its main uses include:
1. Enzyme labeling reagent: can be combined with alkaline phosphatase (alkaline phosphatase) to detect the presence of proteins, nucleic acids or other biological molecules.
2. chemiluminescence detection: as a substrate, it will produce blue, purple or red precipitate after reaction with alkaline phosphatase, which can be detected by visible light or chemiluminescence.
The method for preparing 5-bromo-4-chloro-3-indolyl sodium phosphate is generally as follows:
1. Prepare 5-bromo-4-chloro-3-indolyl chloride (5-Bromo-4-chloro-3-indolyl chloride).
2.5-bromo -4-chloro-3-indolyl chloride is reacted with tetraethyl phosphate (tetraethyl phosphate) in an organic solvent to generate 5-bromo -4-chloro-3-indolyl tetraethyl phosphate (5-Bromo-4-chloro-3-indolyl phosphate tetraethyl ester).
3. Finally, the obtained 5-bromo-4-chloro-3-indolyl phosphate tetraethyl ester was hydrolyzed to 5-bromo-4-chloro-3-indolyl sodium phosphate with tetraacetic acid hydrate (tetrahydrouridine).
However, there are some problems with the safety information about 5-bromo-4-chloro-3-indolyl sodium phosphate. Because its solution will be decomposed in a high humidity environment, it may cause the release of toxic gases or vapors, so it needs to be handled carefully and ensure good ventilation. Avoid contact with skin and eyes during use. When contact occurs, rinse with plenty of water immediately and seek medical treatment. In addition, the use and disposal of chemical reagents should be carried out in accordance with laboratory safety standards and specifications.
1. appearance: white solid powder.
2. Solubility: Soluble in polar solvents such as water, methanol and ethanol.
3. stability: stable in dry and anhydrous environment, but will gradually decompose in high humidity environment.
5-Bromo-4-chloro-3-indolyl sodium phosphate is usually used in biological experiments such as enzyme labeling reagents and chemiluminescence detection. Its main uses include:
1. Enzyme labeling reagent: can be combined with alkaline phosphatase (alkaline phosphatase) to detect the presence of proteins, nucleic acids or other biological molecules.
2. chemiluminescence detection: as a substrate, it will produce blue, purple or red precipitate after reaction with alkaline phosphatase, which can be detected by visible light or chemiluminescence.
The method for preparing 5-bromo-4-chloro-3-indolyl sodium phosphate is generally as follows:
1. Prepare 5-bromo-4-chloro-3-indolyl chloride (5-Bromo-4-chloro-3-indolyl chloride).
2.5-bromo -4-chloro-3-indolyl chloride is reacted with tetraethyl phosphate (tetraethyl phosphate) in an organic solvent to generate 5-bromo -4-chloro-3-indolyl tetraethyl phosphate (5-Bromo-4-chloro-3-indolyl phosphate tetraethyl ester).
3. Finally, the obtained 5-bromo-4-chloro-3-indolyl phosphate tetraethyl ester was hydrolyzed to 5-bromo-4-chloro-3-indolyl sodium phosphate with tetraacetic acid hydrate (tetrahydrouridine).
However, there are some problems with the safety information about 5-bromo-4-chloro-3-indolyl sodium phosphate. Because its solution will be decomposed in a high humidity environment, it may cause the release of toxic gases or vapors, so it needs to be handled carefully and ensure good ventilation. Avoid contact with skin and eyes during use. When contact occurs, rinse with plenty of water immediately and seek medical treatment. In addition, the use and disposal of chemical reagents should be carried out in accordance with laboratory safety standards and specifications.
Last Update：2024-04-09 21:54:55
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