1028-40-6
3-(4-CHLORO-PHENYL)-2-MERCAPTO-3H-QUINAZOLIN-4-ONE
CAS: 1028-40-6
Molecular Formula: C14H9ClN2OS
1028-40-6 - Names and Identifiers
| Name | 3-(4-CHLORO-PHENYL)-2-MERCAPTO-3H-QUINAZOLIN-4-ONE |
| Synonyms | 3-(4-chlorophenyl)-2-thioxo-1H-quinazolin-4-one 3-(4-CHLORO-PHENYL)-2-MERCAPTO-3H-QUINAZOLIN-4-ONE 3-(4-chlorophenyl)-2-sulfanylidene-1H-quinazolin-4-one 3-(4-Chlorophenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one 3-(4-chlorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one 3-(4-Chlorophenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone 4(1H)-Quinazolinone,3-(4-chlorophenyl)-2,3-dihydro-2-thioxo- |
| CAS | 1028-40-6 |
| InChI | InChI=1/C14H9ClN2OS/c15-9-5-7-10(8-6-9)17-13(18)11-3-1-2-4-12(11)16-14(17)19/h1-8H,(H,16,19) |
1028-40-6 - Physico-chemical Properties
| Molecular Formula | C14H9ClN2OS |
| Molar Mass | 288.75 |
| Density | 1.5g/cm3 |
| Boling Point | 457.3°C at 760 mmHg |
| Flash Point | 230.4°C |
| Vapor Presure | 1.5E-08mmHg at 25°C |
| Refractive Index | 1.753 |
1028-40-6 - Introduction
3-(4-Chloro-phenyl) -2-thio-2, 3-dihydro-1H-quinazolin-4-one is an organic compound with a variety of properties and applications.
Nature:
-Appearance: A white solid.
-Molecular formula: C16H11ClN2OS.
-Melting point: about 170-174°C.
-Solubility: Soluble in organic solvents such as ethanol, chloroform, dichloromethane, etc., insoluble in water.
-Stability: relatively stable at room temperature.
Use:
-chemical reagents: commonly used in organic synthesis reactions, such as thiol reaction, ketonization reaction.
-Drug intermediates: can be used to synthesize drugs, such as antidepressants, antiepileptic drugs, etc.
-Pesticide intermediates: can be used to synthesize pesticides, with insecticidal, bactericidal and other effects.
Preparation Method:
3-(4-chloro-phenyl)-2-thio-2, 3-dihydro -1H-quinazolin -4-one synthesis method has a variety of, the following is one of the commonly used methods:
4-chlorobenzaldehyde and methyl thioacetate are reacted to obtain 4-(4-chlorophenyl)-1,3-dihydro-3-thioquinazol-2-one, which is then hydrogenated with 2,3-diazetidinone to obtain the target product 3-(4-chloro-phenyl)-2-thio-2, 3-Dihydro-1H-quinazolin-4-one.
Safety Information:
3-(4-Chloro-phenyl) -2-thio-2, 3-dihydro-1H-quinazolin-4-one is a chemical reagent with certain risks.
-Need to operate in a well-ventilated place, avoid contact with skin and eyes.
-Avoid inhaling its dust or gas. If you accidentally come into contact with it, rinse it with plenty of water immediately and seek medical help.
-Observe relevant safety procedures during storage and handling, and carefully read the safety data sheet (SDS) of the chemical before handling.
-It is strictly forbidden to mix it with incompatible substances to avoid dangerous reactions.
Nature:
-Appearance: A white solid.
-Molecular formula: C16H11ClN2OS.
-Melting point: about 170-174°C.
-Solubility: Soluble in organic solvents such as ethanol, chloroform, dichloromethane, etc., insoluble in water.
-Stability: relatively stable at room temperature.
Use:
-chemical reagents: commonly used in organic synthesis reactions, such as thiol reaction, ketonization reaction.
-Drug intermediates: can be used to synthesize drugs, such as antidepressants, antiepileptic drugs, etc.
-Pesticide intermediates: can be used to synthesize pesticides, with insecticidal, bactericidal and other effects.
Preparation Method:
3-(4-chloro-phenyl)-2-thio-2, 3-dihydro -1H-quinazolin -4-one synthesis method has a variety of, the following is one of the commonly used methods:
4-chlorobenzaldehyde and methyl thioacetate are reacted to obtain 4-(4-chlorophenyl)-1,3-dihydro-3-thioquinazol-2-one, which is then hydrogenated with 2,3-diazetidinone to obtain the target product 3-(4-chloro-phenyl)-2-thio-2, 3-Dihydro-1H-quinazolin-4-one.
Safety Information:
3-(4-Chloro-phenyl) -2-thio-2, 3-dihydro-1H-quinazolin-4-one is a chemical reagent with certain risks.
-Need to operate in a well-ventilated place, avoid contact with skin and eyes.
-Avoid inhaling its dust or gas. If you accidentally come into contact with it, rinse it with plenty of water immediately and seek medical help.
-Observe relevant safety procedures during storage and handling, and carefully read the safety data sheet (SDS) of the chemical before handling.
-It is strictly forbidden to mix it with incompatible substances to avoid dangerous reactions.
Last Update：2024-04-09 15:17:50
