1044560-96-4
(R)-1-Cbz-3-aminopiperidine
CAS: 1044560-96-4
Molecular Formula: C13H18N2O2
1044560-96-4 - Names and Identifiers
| Name | (R)-1-Cbz-3-aminopiperidine |
| Synonyms | (R)-1-Cbz-3-aminopiperidine (R)-N-CBZ-3-AMINO-PIPERIDINE (R)-3-amino-1-n-cbz-piperidine (R)-3-AMINO-1-N-CBZ-PIPERIDINE (R)-1-CBZ-3-AMinopiperidine-HCl (r)-benzyl 3-aminopiperidine-1-carboxylate (R)-BENZYL-3-AMINOPIPERIDINE-1-CARBOXYLATE benzyl (3r)-3-aminopiperidine-1-carboxylate Benzyl (3R)-3-aminopiperidine-1-carboxylate (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER (R)-benzyl 3-aminopiperidine-1-carboxylate hydrochloride |
| CAS | 1044560-96-4 |
| InChI | InChI:1S/C13H18N2O2/c14-12-7-4-8-15(9-12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,14H2 |
1044560-96-4 - Physico-chemical Properties
| Molecular Formula | C13H18N2O2 |
| Molar Mass | 234.29 |
| Density | 1.151±0.06 g/cm3(Predicted) |
| Boling Point | 367.2±42.0 °C(Predicted) |
| pKa | 10.33±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| MDL | MFCD05864625 |
1044560-96-4 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29333990 |
1044560-96-4 - Introduction
(R)-1-Cbz-3-aminopiperidine is an organic compound having the formula C16H15N3O2.
Nature:
(R)-1-Cbz-3-aminopiperidine as a white or off-white crystalline solid. It has good solubility, soluble in common organic solvents such as methanol, ethanol and dimethylformamide. This compound has good chemical stability and can be stored for a long time at room temperature.
Use:
(R)-1-Cbz-3-aminopiperidine is a commonly used synthetic intermediate. It can be used as a synthetic raw material for drugs and pesticides, and is widely used in the fields of medicinal chemistry and organic synthesis. In addition, it can also be used to synthesize protecting groups for proteins and polypeptides.
Preparation Method:
The preparation method of (R)-1-Cbz-3-aminopiperidine is relatively simple, and can usually be completed by introducing amino and carbamic acid benzoyl (Cbz) protecting groups on the piperidine molecule. The specific preparation method can refer to the relevant literature or literature database.
Safety Information:
(R)-1-Cbz-3-aminopiperidine has low toxicity under general conditions, but it is still necessary to pay attention to safe operation. Wear appropriate personal protective equipment to avoid contact with skin and eyes. Avoid inhaling its dust or vapor, and ensure that the operation is carried out in a well-ventilated place. In case of contact, rinse immediately with water and seek medical help. When stored, it should be kept in a dry, cool place, away from fire and flammable materials.
Nature:
(R)-1-Cbz-3-aminopiperidine as a white or off-white crystalline solid. It has good solubility, soluble in common organic solvents such as methanol, ethanol and dimethylformamide. This compound has good chemical stability and can be stored for a long time at room temperature.
Use:
(R)-1-Cbz-3-aminopiperidine is a commonly used synthetic intermediate. It can be used as a synthetic raw material for drugs and pesticides, and is widely used in the fields of medicinal chemistry and organic synthesis. In addition, it can also be used to synthesize protecting groups for proteins and polypeptides.
Preparation Method:
The preparation method of (R)-1-Cbz-3-aminopiperidine is relatively simple, and can usually be completed by introducing amino and carbamic acid benzoyl (Cbz) protecting groups on the piperidine molecule. The specific preparation method can refer to the relevant literature or literature database.
Safety Information:
(R)-1-Cbz-3-aminopiperidine has low toxicity under general conditions, but it is still necessary to pay attention to safe operation. Wear appropriate personal protective equipment to avoid contact with skin and eyes. Avoid inhaling its dust or vapor, and ensure that the operation is carried out in a well-ventilated place. In case of contact, rinse immediately with water and seek medical help. When stored, it should be kept in a dry, cool place, away from fire and flammable materials.
Last Update：2024-04-09 20:52:54
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