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104682-97-5

2-Propenoic acid, 3-(1H-indol-7-yl)-, Methyl ester

CAS: 104682-97-5

Molecular Formula: C12H11NO2

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104682-97-5 - Names and Identifiers

Name 2-Propenoic acid, 3-(1H-indol-7-yl)-, Methyl ester
Synonyms Methyl 3-(1H-indol-7-yl)acrylate
(E)-Methyl 3-(1H-indol-7-yl)acrylate
4-(1H-indol-7-yl)-1-Methoxybut-3-en-2-one
Methyl (2E)-3-(1H-indol-7-yl)prop-2-enoate
3-(1H-indol-7-yl)-2-propenoic acid Methyl ester
2-Propenoic acid, 3-(1H-indol-7-yl)-, Methyl ester
CAS 104682-97-5

104682-97-5 - Physico-chemical Properties

Molecular FormulaC12H11NO2
Molar Mass201.22
Boling Point
Storage ConditionRoom Temprature

104682-97-5 - Introduction

Methyl 3-(1H-indol-7-yl)-2-acrylate is an organic compound with the chemical formula C13H13NO2. It is a colorless to pale yellow liquid with a special aroma. The following is a detailed description of the properties, uses, preparation and safety information of 3-(1H-indol-7-yl)-2-acrylic acid methyl ester:

Nature:
-Appearance: colorless or light yellow liquid
-Molecular weight: 215.25g/mol
-melting point: about -50 ℃
-Boiling point: about 228-230 ℃
-Density: 1.14 g/mL
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and benzene

Use:
Methyl 3-(1H-indol-7-yl)-2-acrylate is mainly used in the field of organic synthesis.
-As a reagent or intermediate in organic synthesis, it participates in the synthesis of compounds with pharmaceutical activity.
-In the field of medicine, it can be used to prepare diethylcarteroamine (Diethylcarbamazine), which is a drug widely used in anti-parasitic treatment.

Preparation Method:
The preparation method of 3-(1H-indol-7-yl)-2-acrylic acid methyl ester can be carried out by the following steps:
1. Indole is reacted with methyl acrylate (methyl acrylate) in the presence of an acid catalyst such as sulfuric acid.
2. Heat the reaction mixture to promote the reaction.
3. Filtration and crystallization gave a crystalline product of methyl 3-(1H-indol-7-yl)-2-propenoate.

Safety Information:
3-(1H-indol-7-yl)-2-acrylic acid methyl ester is an organic compound and has certain safety risks.
-low toxicity: long-term exposure or inhalation may have a certain impact on human health, should be used with caution.
-Irritation: May cause irritation to eyes, skin and respiratory tract. Immediately rinse with water after contact and seek medical attention.
-Protective measures: Wear appropriate personal protective equipment such as goggles, gloves and masks when using.

This information is intended to provide general guidance, and specific use and handling should be evaluated and controlled according to actual conditions and relevant safety regulations. Always observe safety practices when using or handling methyl 3-(1H-indol-7-yl)-2-acrylate.
Last Update:2024-04-09 02:00:40
104682-97-5
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Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Methyl3-(1H-indol-7-yl)acrylate Request for quotation
CAS: 104682-97-5
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 2-Propenoic acid, 3-(1H-indol-7-yl)-, Methyl ester Visit Supplier Webpage Request for quotation
CAS: 104682-97-5
Tel: 18301782025
Email: 3008007409@qq.com
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QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Methyl3-(1H-indol-7-yl)acrylate Request for quotation
CAS: 104682-97-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 2-Propenoic acid, 3-(1H-indol-7-yl)-, Methyl ester Visit Supplier Webpage Request for quotation
CAS: 104682-97-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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104682-97-5
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