104706-47-0
(R)-3-hydroxypyrrolidine hydrochloride
CAS: 104706-47-0
Molecular Formula: C4H10ClNO
104706-47-0 - Names and Identifiers
104706-47-0 - Physico-chemical Properties
| Molecular Formula | C4H10ClNO |
| Molar Mass | 123.58 |
| Melting Point | 104-107°C(lit.) |
| Boling Point | 224.7℃ at 760 mmHg |
| Specific Rotation(α) | -7.6°(20/D, c=3,5, CH3OH) |
| Solubility | Soluble in DMSO. |
| Appearance | Bright brown crystal |
| Color | Pale Brown |
| BRN | 4450078 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | -7.8 ° (C=3.5, MeOH) |
| MDL | MFCD00191570 |
104706-47-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R38 - Irritating to the skin R37 - Irritating to the respiratory system |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29339900 |
104706-47-0 - Reference Information
| overview | (R)-3-hydroxypyrrolidine hydrochloride can be used to prepare dafenacin hydrobromide, a selective muscarinic M3 receptor antagonist developed by Swiss Novartis Company. it was first listed in Germany in 2005 and is clinically used to treat overactive bladder such as urinary incontinence, urgency and frequent urination. |
| Application | (R)-3-hydroxypyrrolidine hydrochloride is a heterocyclic organic substance that can be used as a pharmaceutical intermediate. |
| Preparation | (R)-3-hydroxypyrrolidine hydrochloride is a pyrrole derivative, which can be obtained by decarboxylation of trans-4-hydroxy-L-proline as raw material. |
Last Update：2024-04-09 20:52:54
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