| Molecular Formula | C15H12N2O7 |
| Molar Mass | 332.27 |
| Density | 1.606±0.06 g/cm3(Predicted) |
| Boling Point | 660.5±55.0 °C(Predicted) |
| Solubility | DMSO : 42 mg/mL |
| pKa | 2.95±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.01 ml | 15.048 ml | 30.097 ml |
| 5 mM | 0.602 ml | 3.01 ml | 6.019 ml |
| 10 mM | 0.301 ml | 1.505 ml | 3.01 ml |
| 5 mM | 0.06 ml | 0.301 ml | 0.602 ml |
| biological activity | Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3) is a Thalidomide-based Cereblon (CRBN) ligand that can be used to recruit CRBN proteins. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand of the protein through a connector to form a PROTACs (Proteolysis Targeting Chimera). |
| target | TargetValue CRBN () |
| Target | Value |
| Use | A ligand for E3 ubiquitin ligase in PROTAC technology. |